catalog number :
MBS9353445
products type :
ELISA Kit
products full name :
Rat RNA-Binding Protein Musashi Homolog 1 (MSI1) ELISA Kit
products short name :
[RNA-Binding Protein Musashi Homolog 1 (MSI1)]
other names :
[RNA-binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 1; musashi RNA binding protein 1]
products gene name :
[MSI1]
other gene names :
[MSI1; MSI1; Musashi-1]
uniprot entry name :
MSI1H_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/mL. Sensitivity: 0.1ng/mL
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MSI1 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_002433.1
ncbi gb acc num :
NM_002442.3
ncbi mol weight :
39,125 Da
ncbi pathways :
MRNA Surveillance Pathway (193328); MRNA Surveillance Pathway (193184)
ncbi summary :
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008]
uniprot summary :
Musashi-1: RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'- GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'- [GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system. Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines. Belongs to the Musashi family. Protein type: RNA-binding. Chromosomal Location of Human Ortholog: 12q24. Cellular Component: cytoplasm; nucleus; polysome. Molecular Function: nucleotide binding; poly(U) binding; RNA binding. Biological Process: nervous system development
size4 :
10x96-Strip-Wells