ELISA/assay

Monkey Interferon-Induced GTP-Binding Protein MX1 (MX1) ELISA Kit

MBS9352295

48-Strip-Wells

470 USD

ELISA Kit

Monkey Interferon-Induced GTP-Binding Protein MX1 (MX1) ELISA Kit

[Interferon-Induced GTP-Binding Protein MX1 (MX1)]

[interferon-induced GTP-binding protein Mx1 isoform b; Interferon-induced GTP-binding protein Mx1; interferon-induced GTP-binding protein Mx1; MX dynamin like GTPase 1; Interferon-induced protein p78; IFI-78K]

[MX1]

[MX1; MX1; MX; MxA; IFI78; IFI-78K; IFI-78K]

MX1_HUMAN

Monkey

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MX1 (hereafter termed "analyte") in undiluted original Monkey body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

544711185

NP_001269849.1

NM_001282920.1

55,661 Da

Antiviral Mechanism By IFN-stimulated Genes Pathway (1269316); Cytokine Signaling In Immune System Pathway (1269310); ISG15 Antiviral Mechanism Pathway (1269317); Immune System Pathway (1269170); Influenza A Pathway (217173); Influenza A Pathway (217150); Interferon Signaling Pathway (1269311); Interferon Alpha/beta Signaling Pathway (1269312); Measles Pathway (213306); Measles Pathway (213277)

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

MX1: Dynamin-like GTPase acting as a cell-autonomous host restriction factor against many viral pathogens. Shows activity against influenza viruses, rhabdovirus VSV, bunyavirus LACV, Thogoto virus, measles virus, Hantaan virus, Coxsackie virus CVB, Rift Valley fever virus RVFV, hepatitis B virus HBV, and Crimean- Congo hemorrhagic fever virus CCHFV. Belongs to the dynamin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Apoptosis; Hydrolase. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: cytoplasm; cytosol; endoplasmic reticulum membrane; nuclear membrane; perinuclear region of cytoplasm. Molecular Function: GTP binding; GTPase activity; protein binding. Biological Process: apoptosis; cytokine and chemokine mediated signaling pathway; defense response; defense response to virus; innate immune response; metabolic process; negative regulation of viral genome replication; response to virus; signal transduction

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095