product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Myeloid cell surface antigen CD33, CD33 ELISA Kit
catalog :
MBS934912
quantity :
48-Strip-Wells
price :
510 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS934912
products type :
ELISA Kit
products full name :
Human Myeloid cell surface antigen CD33, CD33 ELISA Kit
products short name :
CD33 molecule
products name syn :
Human Myeloid cell surface antigen CD33 (CD33) ELISA kit; FLJ00391; SIGLEC-3; SIGLEC3; p67; CD33 antigen; CD33 antigen (gp67) ; CD33 molecule
other names :
myeloid cell surface antigen CD33 isoform 2; Myeloid cell surface antigen CD33; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; CD33 molecule; Sialic acid-binding Ig-like lectin 3; Siglec-3; gp67; CD_antigen: CD33
products gene name :
CD33
other gene names :
CD33; CD33; p67; SIGLEC3; SIGLEC-3; SIGLEC3; Siglec-3
uniprot entry name :
CD33_HUMAN
reactivity :
Human
sequence length :
364
specificity :
This assay has high sensitivity and excellent specificity for detection of human CD33. No significant cross-reactivity or interference between human CD33 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 125 pg/ml -8000 pg/ml. Sensitivity: 31.25 pg /ml.
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
products description :
Principle of the Assay This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CD33 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CD33 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CD33 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CD33 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi gi num :
130980072
ncbi acc num :
NP_001076087.1
ncbi gb acc num :
NM_001082618.1
uniprot acc num :
P20138
ncbi mol weight :
39,825 Da
ncbi pathways :
Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489)
uniprot summary :
CD33: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 19q13.3. Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane. Molecular Function: protein binding; receptor activity; carbohydrate binding. Biological Process: negative regulation of cell proliferation; cell-cell signaling; cell adhesion; signal transduction
size1 :
48-Strip-Wells
price1 :
510 USD
size2 :
96-Strip-Wells
price2 :
725
size3 :
5x96-Strip-Wells
price3 :
2565
size4 :
10x96-Strip-Wells
price4 :
4800
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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