Cat Heat Shock Protein 72 (HSP72) ELISA Kit | MyBioSource MBS9348053 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Cat Heat Shock Protein 72 (HSP72) ELISA Kit

catalog :

MBS9348053

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9348053

products type :

ELISA Kit

products full name :

Cat Heat Shock Protein 72 (HSP72) ELISA Kit

products short name :

[Heat Shock Protein 72 (HSP72)]

other names :

[heat shock 70 kDa protein 1A; Heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A; heat shock protein family A (Hsp70) member 1A; Heat shock 70 kDa protein 1; HSP70-1]

products gene name :

[HSP72]

other gene names :

[HSPA1A; HSPA1A; HSP72; HSPA1; HSP70I; HSP70-1; HSP70.1; HSP70-1A; HEL-S-103; HSPA1; HSX70; HSP70.1]

uniprot entry name :

HS71A_HUMAN

reactivity :

Cat

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HSP72 (hereafter termed "analyte") in undiluted original Cat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

194248072

ncbi acc num :

NP_005336.3

ncbi gb acc num :

NM_005345.5

ncbi mol weight :

63,937 Da

ncbi pathways :

AUF1 (hnRNP D0) Binds And Destabilizes MRNA Pathway (1269726); Antigen Processing And Presentation Pathway (83074); Antigen Processing And Presentation Pathway (485); Apoptosis Modulation By HSP70 Pathway (198877); Attenuation Phase Pathway (1270424); Cellular Response To Heat Stress Pathway (1270421); Cellular Responses To Stress Pathway (1270414); Disease Pathway (1268854); Endocytosis Pathway (102279); Endocytosis Pathway (102181)

ncbi summary :

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]

uniprot summary :

HSP70: a critical chaperone protein that has a high affinity for unfolded polypeptide chains. It binds extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In cooperation with other chaperones, hsp70 stabilizes preexistent proteins against aggregation and mediates the folding of newly translated polypeptides in the cytosol as well as within organelles. Mitochondrial HSP70 is crucial to the import process: mutant forms of HSP70 fail to import precursor proteins. Is anti-apoptotic in sympathetic neurones and mediates this effect primarily by suppressing c-Jun transcriptional signalling. Interacts with tau protein and mediates proper folding of tau. Can promote the degradation of tau protein. Triptolide, a potential therapeutic agent for progression/metastasis of pancreatic cancer, causes pancreatic cancer cell death by induction of apoptosis, an effect mediated by the inhibition of HSP70. Protein type: Heat shock protein; Motility/polarity/chemotaxis; Chaperone. Chromosomal Location of Human Ortholog: 6p21.3. Cellular Component: centriole; cytoplasm; cytosol; focal adhesion; inclusion body; mitochondrion; nucleoplasm; perinuclear region of cytoplasm; ubiquitin ligase complex. Molecular Function: ATP binding; ATPase activity; ATPase activity, coupled; enzyme binding; G-protein-coupled receptor binding; heat shock protein binding; histone deacetylase binding; protein binding; receptor binding; ubiquitin protein ligase binding; unfolded protein binding; viral receptor activity. Biological Process: activation of NF-kappaB transcription factor; ATP metabolic process; entry of virus into host cell; gene expression; negative regulation of protein ubiquitination; positive regulation of interleukin-8 production; protein refolding; protein stabilization; regulation of mRNA stability; regulation of protein ubiquitination

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095