Mouse Bile Acid-CoA:Amino Acid N-Acyltransferase (BAAT) ELISA Kit | MyBioSource MBS9347865 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Bile Acid-CoA:Amino Acid N-Acyltransferase (BAAT) ELISA Kit

catalog :

MBS9347865

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9347865

products type :

ELISA Kit

products full name :

Mouse Bile Acid-CoA:Amino Acid N-Acyltransferase (BAAT) ELISA Kit

products short name :

[Bile Acid-CoA:Amino Acid N-Acyltransferase (BAAT)]

other names :

[bile acid-CoA:amino acid N-acyltransferase; Bile acid-CoA:amino acid N-acyltransferase; bile acid-CoA:amino acid N-acyltransferase; bile acid-CoA:amino acid N-acyltransferase; Glycine N-choloyltransferase; Long-chain fatty-acyl-CoA hydrolase]

products gene name :

[BAAT]

other gene names :

[BAAT; BAAT; BAT; BACAT; BAT]

uniprot entry name :

BAAT_HUMAN

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of BAAT (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

4502351

ncbi acc num :

NP_001692.1

ncbi gb acc num :

NM_001701.3

ncbi mol weight :

46,299 Da

ncbi pathways :

Bile Acid And Bile Salt Metabolism Pathway (1270040); Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Biosynthesis Of Unsaturated Fatty Acids Pathway (83034); Biosynthesis Of Unsaturated Fatty Acids Pathway (429); Conjugated Bile Acid Biosynthesis, Cholate = Taurocholate/glycocholate Pathway (472628); Conjugated Bile Acid Biosynthesis, Cholate = Taurocholate/glycocholate Pathway (468366); Drug Induction Of Bile Acid Pathway (698755); Metabolic Pathways (132956); Metabolism Pathway (1269956)

ncbi summary :

The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

BAAT: Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs. Defects in BAAT are involved in familial hypercholanemia (FHCA). FHCA is a disorder characterized by elevated serum bile acid concentrations, itching, and fat malabsorption. Belongs to the C/M/P thioester hydrolase family. Protein type: Lipid Metabolism - unsaturated fatty acid biosynthesis; EC 3.1.2.2; Hydrolase; Lipid Metabolism - primary bile acid biosynthesis; Transferase; EC 2.3.1.65; Other Amino Acids Metabolism - taurine and hypotaurine. Chromosomal Location of Human Ortholog: 9q22.3. Cellular Component: cytosol; peroxisomal matrix; peroxisome. Molecular Function: glycine N-choloyltransferase activity; N-acyltransferase activity; palmitoyl-CoA hydrolase activity; protein binding; receptor binding. Biological Process: acyl-CoA metabolic process; bile acid and bile salt transport; bile acid biosynthetic process; bile acid metabolic process; fatty acid metabolic process; glycine metabolic process; liver development; organ regeneration; taurine metabolic process. Disease: Hypercholanemia, Familial

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095