Human Transcriptional Intermediary Factor 1 Beta (TIF1B) ELISA Kit | MyBioSource MBS9347787 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Transcriptional Intermediary Factor 1 Beta (TIF1B) ELISA Kit

catalog :

MBS9347787

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9347787

products type :

ELISA Kit

products full name :

Human Transcriptional Intermediary Factor 1 Beta (TIF1B) ELISA Kit

products short name :

[Transcriptional Intermediary Factor 1 Beta (TIF1B)]

other names :

[transcription intermediary factor 1-beta; Transcription intermediary factor 1-beta; transcription intermediary factor 1-beta; tripartite motif containing 28; E3 SUMO-protein ligase TRIM28 (EC:6.3.2.-); KRAB-associated protein 1; KAP-1; KRAB-interacting protein 1; KRIP-1; Nuclear corepressor KAP-1; RING finger protein 96; Tripartite motif-containing protein 28]

products gene name :

[TIF1B]

other gene names :

[TRIM28; TRIM28; KAP1; TF1B; RNF96; TIF1B; PPP1R157; KAP1; RNF96; TIF1B; TIF1-beta; KAP-1; KRIP-1]

uniprot entry name :

TIF1B_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 62.5pg/ml-2000pg/ml. Sensitivity: 10pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TIF1B (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

5032179

ncbi acc num :

NP_005753.1

ncbi gb acc num :

NM_005762.2

ncbi mol weight :

79,474 Da

ncbi pathways :

C-MYB Transcription Factor Network Pathway (138073); Corticotropin-releasing Hormone Pathway (920957); E2F Transcription Factor Network Pathway (137934); Gene Expression Pathway (1269649); Generic Transcription Pathway (1269650); P53 Pathway (138067)

ncbi summary :

The protein encoded by this gene mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. The protein localizes to the nucleus and is thought to associate with specific chromatin regions. The protein is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]

uniprot summary :

TIF1B: an atypical protein kinase that functions as a transcriptional coactivator. Mediates transcriptional regulation by interaction with the Kruppel-associated box (KRAB) repression domain found in many transcription factors. Binds to the negative regulatory domain of c-Myb and negatively regulates the c-Myb-dependent trans-activation. Localizes to the nucleus and is thought to associate with specific chromatin regions. Phosphorylated in an ATM-dependent manner following double-strand breaks. Its phosphorylation in response to DNA damage leads to chromatin relaxation. A member of the tripartite motif family. The tripartite motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Protein type: Ubiquitin ligase; EC 6.3.2.-; Kinase, protein; Ubiquitin conjugating system; Ligase; Transcription, coactivator/corepressor; Protein kinase, atypical; Nuclear receptor co-regulator; ATYPICAL group; TIF1 family. Chromosomal Location of Human Ortholog: 19q13.4. Cellular Component: nuclear heterochromatin; nucleoplasm; nucleus. Molecular Function: DNA binding; ligase activity; protein binding; protein kinase activity; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; zinc ion binding. Biological Process: convergent extension involved in axis elongation; DNA methylation during embryonic development; DNA repair; embryo implantation; epithelial to mesenchymal transition; gene expression; innate immune response; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of DNA repair; positive regulation of transcription factor import into nucleus; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein amino acid autophosphorylation; protein oligomerization; protein sumoylation; protein ubiquitination; transcription initiation from RNA polymerase II promoter

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095