Human Tyrosine Kinase B (TRKB) ELISA Kit | MyBioSource MBS9346917 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Tyrosine Kinase B (TRKB) ELISA Kit

catalog :

MBS9346917

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9346917

products type :

ELISA Kit

products full name :

Human Tyrosine Kinase B (TRKB) ELISA Kit

products short name :

[Tyrosine Kinase B (TRKB)]

other names :

[tyrosine kinase; Ephrin type-B receptor 4; ephrin type-B receptor 4; EPH receptor B4; Hepatoma transmembrane kinase; Tyrosine-protein kinase TYRO11]

products gene name :

[TRKB]

other gene names :

[EPHB4; EPHB4; HTK; MYK1; TYRO11; HTK; MYK1; TYRO11]

uniprot entry name :

EPHB4_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TRKB (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

495473

ncbi acc num :

AAA20598.1

ncbi mol weight :

45,195 Da

ncbi pathways :

Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (1270303); Developmental Biology Pathway (1270302); EPH-Ephrin Signaling Pathway (1270330); EPH-ephrin Mediated Repulsion Of Cells Pathway (1270334); EPHB Forward Signaling Pathway (138047); EPHB-mediated Forward Signaling Pathway (1270332); Ephrin B Reverse Signaling Pathway (138052); Ephrin Signaling Pathway (1270333)

ncbi summary :

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008]

uniprot summary :

EphB4: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4- mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis. Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. Protein type: Kinase, protein; EC 2.7.10.1; Membrane protein, integral; Protein kinase, tyrosine (receptor); Protein kinase, TK; TK group; Eph family. Chromosomal Location of Human Ortholog: 7q22. Cellular Component: cytosol; extracellular region; integral to plasma membrane; plasma membrane. Molecular Function: ATP binding; ephrin receptor activity; protein binding; transmembrane receptor protein tyrosine kinase activity. Biological Process: angiogenesis; axon guidance; cell adhesion; cell migration during sprouting angiogenesis; ephrin receptor signaling pathway; heart morphogenesis; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095