This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Syntaxin-binding protein 3, STXBP3 ELISA Kit
catalog :
MBS9343381
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS9343381
products type :
ELISA Kit
products full name :
Human Syntaxin-binding protein 3, STXBP3 ELISA Kit
products short name :
[syntaxin binding protein 3]
products name syn :
[Human Syntaxin-binding protein 3 (STXBP3) ELISA kit; MUNC18-3; MUNC18C; PSP; UNC-18C; syntaxin 4 binding protein; syntaxin binding protein 3]
other names :
[syntaxin-binding protein 3; Syntaxin-binding protein 3; syntaxin-binding protein 3; unc18-3; platelet Sec1 protein; protein unc-18 homolog 3; protein unc-18 homolog C; syntaxin 4 binding protein; syntaxin binding protein 3; Platelet Sec1 protein; PSP; Protein unc-18 homolog 3; Unc18-3; Protein unc-18 homolog C; Unc-18C]
products gene name :
[STXBP3]
other gene names :
[STXBP3; STXBP3; PSP; MUNC18C; UNC-18C; MUNC18-3; PSP; Unc18-3; Unc-18C]
uniprot entry name :
STXB3_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV(%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of STXBP3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
118600975
ncbi acc num :
NP_009200.2
ncbi gb acc num :
NM_007269.2
uniprot acc num :
O00186
ncbi mol weight :
67,764 Da
ncbi pathways :
Disinhibition Of SNARE Formation Pathway (106049); Hemostasis Pathway (106028); Insulin Signaling Pathway (198845); Platelet Activation, Signaling And Aggregation Pathway (106034); Response To Elevated Platelet Cytosolic Ca2+ Pathway (106048)
uniprot summary :
STXBP3: a vesicle protein that, together with STX4 and VAMP2, regulates the insulin-dependent movement of GLUT4 and the docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. Reduction in its expression using siRNA impairs insulin-stimulated GLUT4 vesicle exocytosis in 3T3-L1 adipocytes. Phosphorylated by the insulin receptor (InsR) at Tyr521 in vitro, and bound and phosphorylated by the activated InsR within adipocytes and skeletal muscle. Tyrosine phosphorylation on residues Y219 and Y521 correlates with its dissociation from STX4. Phosphorylated by PKC in platelets in response to thrombin stimulation, inhibiting its binding to STX4. Interacts directly with DOC2B at the cell membrane, excluding its interaction with STX4, regulating glucose-stimulated insulin secretion. Belongs to the STXBP/unc-18/SEC1 family. Protein type: Vesicle. Chromosomal Location of Human Ortholog: 1p13.3. Cellular Component: specific granule; basolateral plasma membrane; apical plasma membrane; plasma membrane; cytosol. Molecular Function: protein binding; syntaxin binding; syntaxin-1 binding. Biological Process: platelet activation; negative regulation of calcium ion-dependent exocytosis; insulin secretion; protein heterooligomerization; neutrophil degranulation; protein to membrane docking; brain development; glucose transport; blood coagulation; vesicle docking during exocytosis; response to insulin stimulus
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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