catalog number :
MBS9343377
products type :
ELISA Kit
products full name :
Mouse Zinc finger protein SNAI1, SNAI1 ELISA Kit
products short name :
[snail homolog 1 (Drosophila)]
products name syn :
[Mouse Zinc finger protein SNAI1 (SNAI1) ELISA kit; SLUGH2; SNA; SNAH; dJ710H13.1; snail 1 homolog; snail 1 zinc finger protein; snail 1; zinc finger protein; snail homolog 1 (Drosophila)]
other names :
[zinc finger protein SNAI1; Zinc finger protein SNAI1; zinc finger protein SNAI1; protein sna; snail homolog 1; protein snail homolog 1; snail family zinc finger 1; Protein snail homolog 1; Protein sna]
products gene name :
[SNAI1]
other gene names :
[Snai1; Snai1; Sna; Sna1; Snail; Snail1; AI194338; Sna; Protein sna]
uniprot entry name :
SNAI1_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SNAI1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_035557.1
ncbi gb acc num :
NM_011427.2
ncbi mol weight :
29,190 Da
ncbi pathways :
Adherens Junction Pathway (83267); Adherens Junction Pathway (481)
uniprot summary :
Snail1: a protein of the C2H2-type zinc-finger family that regulates transcription. Involved in embryonic mesoderm formation. Plays a role in the epithelial to mesenchymal transition (EMT). EMT is characterized by decreased levels of the epithelial markers E-cadherin and alpha- and beta-catenin, and increased cellular migration and expression of the mesenchymal markers fibronectin, vimentin, N-cadherin and smooth muscle alpha-actin.E Snail binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. NF-kappaB binds and regulates the snail promoter and is critical for EMT, and inhibition of NF-kappaB activity lowered snail levels and morphologically reversed the EMT. Protein type: C2H2-type zinc finger protein; Transcription factor. Cellular Component: cytoplasm; nucleus. Molecular Function: protein binding; nucleic acid binding; DNA binding; sequence-specific DNA binding; metal ion binding; transcription factor activity; kinase binding. Biological Process: transcription from RNA polymerase II promoter; cell migration; hair follicle morphogenesis; positive regulation of transcription, DNA-dependent; multicellular organismal development; palate development; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; negative regulation of DNA damage response, signal transduction by p53 class mediator; mesoderm formation; epithelial to mesenchymal transition; mesoderm development; negative regulation of transcription, DNA-dependent; positive regulation of cell migration
size4 :
10x96-Strip-Wells