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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Gamma-aminobutyric acid type B receptor subunit 1, GABBR1 ELISA Kit
catalog :
MBS9342923
quantity :
96 Strip Wells
price :
600 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9342923
products type :
ELISA Kit
products full name :
Rat Gamma-aminobutyric acid type B receptor subunit 1, GABBR1 ELISA Kit
products short name :
gamma-aminobutyric acid (GABA) B receptor, 1
products name syn :
Rat Gamma-aminobutyric acid type B receptor subunit 1 (GABBR1) ELISA kit; DAAP-188P13.3; FLJ92613; GABABR1; GABBR1-3; GB1; GPRC3A; dJ271M21.1.1; dJ271M21.1.2; GABA-B receptor; GABAB; subunit 1c; OTTHUMP00000109099; gamma-aminobutyric acid (GABA) B receptor 1; gamma-aminobutyr; gamma-aminobutyric acid (GABA) B receptor; 1
other names :
gamma-aminobutyric acid type B receptor subunit 1; Gamma-aminobutyric acid type B receptor subunit 1; gamma-aminobutyric acid type B receptor subunit 1; gb1; GABABR1; GABA-BR1; GABA-B-R1; GABA-B receptor 1; gamma-aminobutyric acid (GABA) B receptor 1
products gene name :
GABBR1
other gene names :
Gabbr1; Gabbr1; GABA-B receptor 1; GABA-B-R1; GABA-BR1; GABABR1; Gb1
uniprot entry name :
GABR1_RAT
reactivity :
Rat
ncbi gi num :
77404238
ncbi acc num :
NP_112290.2
ncbi gb acc num :
NM_031028.3
uniprot acc num :
Q9Z0U4
ncbi mol weight :
111,534 Da
ncbi pathways :
Activation Of G Protein Gated Potassium Channels Pathway 574472!!Activation Of GABAB Receptors Pathway 574466!!Class C/3 (Metabotropic Glutamate/pheromone Receptors) Pathway 574249!!G Alpha (i) Signalling Events Pathway 574252!!G Protein Gated Potassium Channels Pathway 574471!!GABA B Receptor Activation Pathway 574465!!GABA Receptor Activation Pathway 574464!!GABAergic Synapse Pathway 377244!!GABAergic Synapse Pathway 377129!!GPCR Downstream Signaling Pathway 574250
ncbi summary :
metabotropic G-protein-coupled receptor for gamma-aminobutyric acid (GABA) [RGD, Feb 2006]
uniprot summary :
Function: Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Calcium is required for high affinity binding to GABA. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.1 PublicationManual assertion based on experiment in:Ref.1
size :
96 Strip Wells
price :
600 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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