catalog number :
MBS9342772
products type :
ELISA Kit
products full name :
Human Upstream stimulatory factor 1, USF1 ELISA Kit
products short name :
[upstream transcription factor 1]
products name syn :
[Human Upstream stimulatory factor 1 (USF1) ELISA kit; RP11-544M22.5; FCHL; FCHL1; HYPLIP1; MLTF; MLTFI; UEF; bHLHb11; OTTHUMP00000029693; major late transcription factor 1; upstream stimulatory factor 1; upstream transcription factor 1]
other names :
[upstream stimulatory factor 1 isoform 1; Upstream stimulatory factor 1; upstream stimulatory factor 1; major late transcription factor 1; class B basic helix-loop-helix protein 11; upstream transcription factor 1; Class B basic helix-loop-helix protein 11; bHLHb11; Major late transcription factor 1]
products gene name :
[USF1]
other gene names :
[USF1; USF1; UEF; FCHL; MLTF; FCHL1; MLTFI; HYPLIP1; bHLHb11; BHLHB11; USF; bHLHb11]
uniprot entry name :
USF1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of UPAR (hereafter termed "analyte") in undiluted original Mouse body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001263302.1
ncbi gb acc num :
NM_001276373.1
ncbi mol weight :
33,538 Da
ncbi pathways :
Signaling Mediated By P38-alpha And P38-beta Pathway (138012)
ncbi summary :
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21. [provided by RefSeq, Feb 2013]
uniprot summary :
USF1: Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5 -CACGTG-3 ) that is found in a variety of viral and cellular promoters. Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an homodimer or a heterodimer (USF1/USF2). Interacts with varicella-zoster virus IE62 protein. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 1q22-q23. Cellular Component: nucleoplasm; transcription factor complex; nucleus. Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein homodimerization activity; enzyme binding; protein heterodimerization activity; sequence-specific DNA binding; histone deacetylase binding; double-stranded DNA binding; bHLH transcription factor binding; protein kinase binding. Biological Process: transcription from RNA polymerase II promoter; lipid homeostasis; late viral mRNA transcription; glucose metabolic process; glucose homeostasis; regulation of transcription from RNA polymerase II promoter; negative regulation of fibrinolysis; cellular response to insulin stimulus; regulation of transcription from RNA polymerase II promoter by glucose; response to hypoxia; regulation of transcription by carbon catabolites; positive regulation of transcription from RNA polymerase II promoter by glucose; positive regulation of transcription from RNA polymerase II promoter; response to UV. Disease: Hyperlipidemia, Combined, 1
size4 :
10x96-Strip-Wells