catalog number :
MBS9342743
products type :
ELISA Kit
products full name :
Bovine Exosome complex component RRP45, EXOSC9 ELISA Kit
products short name :
[exosome component 9]
products name syn :
[Bovine Exosome complex component RRP45 (EXOSC9) ELISA kit; PM/Scl-75; PMSCL1; RRP45; Rrp45p; p5; p6; P75 polymyositis-scleroderma overlap syndrome associated autoantigen; PMSCL autoantigen; 75kD; autoantigen PM/Scl 1; polymyositis/scleroderma autoantigen 1 (75; exosome component 9]
other names :
[exosome complex component RRP45; Exosome complex component RRP45; exosome complex component RRP45; exosome complex exonuclease RRP45; exosome component 9<; Exosome component 9]
products gene name :
[EXOSC9]
other gene names :
[EXOSC9; EXOSC9]
uniprot entry name :
EXOS9_BOVIN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of EXOSC9 (hereafter termed "analyte") in undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001030225.1
ncbi gb acc num :
NM_001035053.1
ncbi mol weight :
49,150 Da
ncbi pathways :
Exosome, Eukaryotes Pathway (583147); Exosome, Eukaryotes Pathway (468397); RNA Degradation Pathway (117266); RNA Degradation Pathway (116127)
uniprot summary :
Function: Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC9 binds to ARE-containing RNAs
size4 :
10x96-Strip-Wells