catalog number :
MBS9342320
products type :
ELISA Kit
products full name :
Mouse Protein-lysine 6-oxidase, LOX ELISA Kit
products short name :
[lysyl oxidase]
products name syn :
[Mouse Protein-lysine 6-oxidase (LOX) ELISA kit; MGC105112; protein-lysine 6-oxidase; lysyl oxidase]
other names :
[protein-lysine 6-oxidase preproprotein; Protein-lysine 6-oxidase; protein-lysine 6-oxidase; ras recision; ras excision protein; lysyl oxidase; Lysyl oxidase; Ras excision protein]
products gene name :
[LOX]
other gene names :
[Lox; Lox; rrg; TSC-160; AI893619; Rrg]
uniprot entry name :
LYOX_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV(%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LOX (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001273110.1
ncbi gb acc num :
NM_001286181.1
ncbi mol weight :
46,701 Da
ncbi summary :
This gene encodes a precursor protein that belongs to the lysyl oxidase family of proteins. The secreted proprotein is proteolytically processed to an active mature peptide and a propeptide. This propeptide is thought to function in tumor suppression by inhibiting the Ras signaling pathway. The active enzyme plays a role in cross-linking of collagen and elastin and is essential for development of cardiovascular and respiratory systems, and development of skin and connective tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
uniprot summary :
LOX: Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression. Belongs to the lysyl oxidase family. Protein type: EC 1.4.3.13; Secreted; Oxidoreductase; Secreted, signal peptide. Cellular Component: proteinaceous extracellular matrix; collagen; extracellular region; nucleus. Molecular Function: protein binding; copper ion binding; protein-lysine 6-oxidase activity; metal ion binding; oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor; oxidoreductase activity. Biological Process: blood vessel development; elastic fiber assembly; collagen fibril organization; wound healing; response to steroid hormone stimulus; response to hormone stimulus; lung development
size4 :
10x96-Strip-Wells