catalog number :
MBS9342250
products type :
ELISA Kit
products full name :
Human Nucleolysin TIAR, TIAL1 ELISA Kit
products short name :
[TIA1 cytotoxic granule-associated RNA binding protein-like 1]
products name syn :
[Human Nucleolysin TIAR (TIAL1) ELISA kit; MGC33401; TCBP; TIAR; T-cluster binding protein; TIA-1 related protein; TIA-1-related nucleolysin; TIA1 cytotoxic granule-associated RNA-binding protein-like 1; aging-associated gene 7 protein; TIA1 cytotoxic granule-associated RNA binding protein-like 1]
other names :
[nucleolysin TIAR isoform 2; Nucleolysin TIAR; nucleolysin TIAR; T-cluster binding protein; TIA-1-related nucleolysin; aging-associated gene 7 protein; TIA1 cytotoxic granule-associated RNA binding protein-like 1; TIA-1-related protein]
products gene name :
[TIAL1]
other gene names :
[TIAL1; TIAL1; TCBP; TIAR]
uniprot entry name :
TIAR_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TIAL1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001029097.1
ncbi gb acc num :
NM_001033925.1
ncbi mol weight :
41,591 Da
ncbi summary :
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing. [provided by RefSeq, Jul 2008]
uniprot summary :
TIAL1: a member of a family of RNA-binding proteins that possesses nucleolytic activity. A cytotoxic T cell granule-associated protein that has been shown to bind specifically to poly(A) homopolymers and to fragment DNA in permeabilized target cells. Members of this protein family may be involved in the induction of apoptosis. Two splice variant isoforms have been described. Protein type: Apoptosis; RNA-binding. Chromosomal Location of Human Ortholog: 10q. Cellular Component: stress granule; lysosome; cytoplasm; nucleus. Molecular Function: RNA binding; nucleotide binding; AU-rich element binding. Biological Process: regulation of transcription from RNA polymerase II promoter; apoptosis; stem cell division; positive regulation of cell proliferation; defense response; germ cell development
size4 :
10x96-Strip-Wells