catalog number :
MBS9342163
products type :
ELISA Kit
products full name :
Human Protein NLRC3, NLRC3 ELISA Kit
products short name :
[NLR family, CARD domain containing 3]
products name syn :
[Human Protein NLRC3 (NLRC3) ELISA kit; CLR16.2; FLJ00348; NOD3; CARD15-like; NOD-like receptor C3; NOD3 protein; caterpiller 16.2; nucleotide-binding oligomerization domain; leucine rich repeat and CARD domain containing 3; NLR family; CARD domain containing 3]
other names :
[protein NLRC3; Protein NLRC3; protein NLRC3; CARD15-like protein; NOD-like receptor C3; caterpiller protein 16.2; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 3; NLR family, CARD domain containing 3; CARD15-like protein; Caterpiller protein 16.2; CLR16.2; Nucleotide-binding oligomerization domain protein 3]
products gene name :
[NLRC3]
other gene names :
[NLRC3; NLRC3; NOD3; CLR16.2; NOD3; CLR16.2]
uniprot entry name :
NLRC3_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NLRC3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_849172.2
ncbi gb acc num :
NM_178844.3
ncbi mol weight :
114,658 Da
ncbi summary :
This gene encodes a NOD-like receptor family member. The encoded protein is a cytosolic regulator of innate immunity. This protein directly interacts with stimulator of interferon genes (STING), to prevent its proper trafficking, resulting in disruption of STING-dependent activation of the innate immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
uniprot summary :
NLRC3: May modulate T-cell activation. Decreases the transcription of genes that are normally up-regulated after T-cell stimulation. Delays degradation of NFKBIA/IKBA. Belongs to the NLRP family. 4 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: cytoplasm. Molecular Function: ATP binding. Biological Process: I-kappaB kinase/NF-kappaB cascade; T cell activation; inhibition of NF-kappaB transcription factor; regulation of protein ubiquitination; response to lipopolysaccharide; negative regulation of I-kappaB kinase/NF-kappaB cascade
size4 :
10x96-Strip-Wells