product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Rat Gamma-aminobutyric acid receptor subunit alpha-1, GABRA1 ELISA Kit
catalog :
MBS9342109
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9342109
products type :
ELISA Kit
products full name :
Rat Gamma-aminobutyric acid receptor subunit alpha-1, GABRA1 ELISA Kit
products short name :
gamma-aminobutyric acid (GABA) A receptor, alpha 1
products name syn :
Rat Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1) ELISA kit; ECA4; EJM; EJM5; ; gamma-aminobutyric acid (GABA) A receptor; alpha 1
other names :
gamma-aminobutyric acid receptor subunit alpha-1; Gamma-aminobutyric acid receptor subunit alpha-1; gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1; gamma-aminobutyric acid A receptor, alpha 1; gamma-aminobutyric acid A receptor, alpha 1; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1; gamma-aminobutyric acid (GABA) A receptor, alpha 1; GABA(A) receptor subunit alpha-1
products gene name :
GABRA1
other gene names :
Gabra1; Gabra1; Gabra-1
uniprot entry name :
GBRA1_RAT
reactivity :
Rat
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 0.5 umol/L - 16 umol/L. Sensitivity: 0.1 umol/L.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GABRA1 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
34328532
ncbi acc num :
NP_899155.1
ncbi gb acc num :
NM_183326.2
uniprot acc num :
P62813
ncbi mol weight :
51,754 Da
ncbi pathways :
GABAergic Synapse Pathway (377244); GABAergic Synapse Pathway (377129); Morphine Addiction Pathway (552694); Morphine Addiction Pathway (554808); Neuroactive Ligand-receptor Interaction Pathway (83445); Neuroactive Ligand-receptor Interaction Pathway (462); Nicotine Addiction Pathway (583273); Nicotine Addiction Pathway (584676); Retrograde Endocannabinoid Signaling Pathway (537882); Retrograde Endocannabinoid Signaling Pathway (539806)
ncbi summary :
subunit of GABAA receptors, which bind benzodiazepines and act as inhibitory ion channels in the brain [RGD, Feb 2006]
uniprot summary :
GABRA1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Defects in GABRA1 are the cause of childhood absence epilepsy type 4 (ECA4). A subtype of idiopathic generalized epilepsy characterized by onset at age 6-7 years, frequent absence seizures (several per day) and bilateral, synchronous, symmetric 3-Hz spike waves on EEG. During adolescence, tonic-clonic and myoclonic seizures may develop. Absence seizures may either remit or persist into adulthood. Defects in GABRA1 are the cause of juvenile myoclonic epilepsy type 5 (EJM5). A subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily. Protein type: Transporter; Transporter, ion channel; Membrane protein, integral; Channel, ligand-gated; Membrane protein, multi-pass. Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction. Molecular Function: chloride channel activity; protein binding; GABA-A receptor activity; GABA receptor activity; benzodiazepine receptor activity; inhibitory extracellular ligand-gated ion channel activity; drug binding. Biological Process: synaptic transmission, GABAergic; chloride transport; gamma-aminobutyric acid signaling pathway
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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