catalog number :
MBS9341940
products type :
ELISA Kit
products full name :
Human WD repeat-containing protein 5, WDR5 ELISA Kit
products short name :
[WD repeat domain 5]
products name syn :
[Human WD repeat-containing protein 5 (WDR5) ELISA kit; BIG-3; SWD3; BMP2-induced 3-kb gene protein; SWD3; Set1c WD40 repeat protein; homolog; WD-repeat protein 5; WD repeat domain 5]
other names :
[WD repeat-containing protein 5; WD repeat-containing protein 5; WD repeat-containing protein 5; WD-repeat protein 5; BMP2-induced 3-kb gene protein; SWD3, Set1c WD40 repeat protein, homolog; cilia and flagella associated protein 89; WD repeat domain 5; BMP2-induced 3-kb gene protein]
products gene name :
[WDR5]
other gene names :
[WDR5; WDR5; SWD3; BIG-3; CFAP89; BIG3]
uniprot entry name :
WDR5_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of WDR5 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_060058.1
ncbi gb acc num :
NM_017588.2
ncbi mol weight :
36,588 Da
ncbi pathways :
Circadian Rhythm Pathway (137978)
ncbi summary :
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
uniprot summary :
WDR5: a WD40 repeat protein. May accelerate osteoblast differentiation. Interacts with HCFC1. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 9q34. Cellular Component: nucleoplasm; histone methyltransferase complex; nucleus; histone acetyltransferase complex. Molecular Function: protein binding; histone lysine N-methyltransferase activity (H3-K4 specific); histone acetyltransferase activity (H4-K16 specific). Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; histone H3-K4 methylation; skeletal development
size4 :
10x96-Strip-Wells