Human Dual specificity protein phosphatase 10, DUSP10 ELISA Kit | MyBioSource MBS9341921 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Dual specificity protein phosphatase 10, DUSP10 ELISA Kit

catalog :

MBS9341921

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9341921

products type :

ELISA Kit

products full name :

Human Dual specificity protein phosphatase 10, DUSP10 ELISA Kit

products short name :

[dual specificity phosphatase 10]

products name syn :

[Human Dual specificity protein phosphatase 10 (DUSP10) ELISA kit; MKP-5; MKP5; dual specificity phosphatase MKP-5; map kinase phosphatase 5; serine/threonine specific protein phosphatase; dual specificity phosphatase 10]

other names :

[dual specificity protein phosphatase 10; Dual specificity protein phosphatase 10; dual specificity protein phosphatase 10; map kinase phosphatase 5; dual specificity phosphatase MKP-5; serine/threonine specific protein phosphatase; mitogen-activated protein kinase phosphatase 5; dual specificity phosphatase 10; Mitogen-activated protein kinase phosphatase 5; MAP kinase phosphatase 5; MKP-5]

products gene name :

[DUSP10]

other gene names :

[DUSP10; DUSP10; MKP5; MKP-5; MKP5; MAP kinase phosphatase 5; MKP-5]

uniprot entry name :

DUS10_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DUSP10 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

6005812

ncbi acc num :

NP_009138.1

ncbi gb acc num :

NM_007207.5

uniprot acc num :

Q9Y6W6

ncbi mol weight :

52,642 Da

ncbi pathways :

ATF-2 Transcription Factor Network Pathway (138006); MAPK Signaling Pathway (198779); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Regulation Of P38-alpha And P38-beta Pathway (137964)

ncbi summary :

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

uniprot summary :

MKP-5: a non-receptor, dual-specificity phosphoprotein phosphatase (DUSP). Different members of the DUSP family show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP10 binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique; it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene. Contains 1 rhodanese domain. Protein type: Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity; EC 3.1.3.16; EC 3.1.3.48. Chromosomal Location of Human Ortholog: 1q41. Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleus. Molecular Function: MAP kinase phosphatase activity; phosphoric monoester hydrolase activity; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; phosphoprotein phosphatase activity. Biological Process: negative regulation of oligodendrocyte differentiation; negative regulation of JNK activity; negative regulation of JNK cascade; regulation of adaptive immune response; response to stress; JNK cascade; oligodendrocyte differentiation; response to lipopolysaccharide; protein amino acid dephosphorylation; inactivation of MAPK activity

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095