catalog number :
MBS9341901
products type :
ELISA Kit
products full name :
Human Dihydrofolate reductase-like protein 1, DHFRL1 ELISA Kit
products short name :
dihydrofolate reductase-like 1
products name syn :
Human Dihydrofolate reductase-like protein 1 (DHFRL1) ELISA kit; DHFRP4; FLJ16119; dihydrofolate reductase pseudogene 4; dihydrofolate reductase-like 1
other names :
dihydrofolate reductase, mitochondrial; Dihydrofolate reductase, mitochondrial; dihydrofolate reductase, mitochondrial; dihydrofolate reductase pseudogene 4; dihydrofolate reductase-like protein 1; dihydrofolate reductase-like 1; Dihydrofolate reductase-like protein 1
products gene name :
DHFRL1
other gene names :
DHFRL1; DHFRL1; DHFRP4; DHFRP4
uniprot entry name :
DYRL1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of DHFRL1 (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_001182572.1
ncbi gb acc num :
NM_001195643.1
ncbi mol weight :
21,620 Da
ncbi pathways :
Folate Biosynthesis Pathway (83018); Folate Biosynthesis Pathway (404); One Carbon Pool By Folate Pathway (83008); One Carbon Pool By Folate Pathway (393)
uniprot summary :
DHFRL1: Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR. Belongs to the dihydrofolate reductase family. Protein type: Mitochondrial; EC 1.5.1.3. Chromosomal Location of Human Ortholog: 3q11.1. Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial inner membrane. Molecular Function: mRNA binding; dihydrofolate reductase activity; NADP binding. Biological Process: tetrahydrofolate metabolic process; tetrahydrofolate biosynthetic process; nucleotide biosynthetic process; one-carbon compound metabolic process; glycine biosynthetic process; thymidine biosynthetic process