ELISA/assay

Mouse MAP kinase-activated protein kinase 2, MAPKAPK2 ELISA Kit

MBS9341712

48-Strip-Wells

470 USD

ELISA Kit

Mouse MAP kinase-activated protein kinase 2, MAPKAPK2 ELISA Kit

[mitogen-activated protein kinase-activated protein kinase 2]

[Mouse MAP kinase-activated protein kinase 2 (MAPKAPK2) ELISA kit; MK2; ; mitogen-activated protein kinase-activated protein kinase 2]

[MAP kinase-activated protein kinase 2; MAP kinase-activated protein kinase 2; MAP kinase-activated protein kinase 2; MAPKAPK-2; MAPKAP kinase 2; MAPK-activated protein kinase 2; MAP kinase-activated protein kinase 2]

[MAPKAPK2]

[Mapkapk2; Mapkapk2; MK2; MK-2; Rps6kc1; AA960234; MAPKAP-K2; Rps6kc1; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2]

MAPK2_MOUSE

Mouse

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Assay Type: Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MAPKAPK2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

45544580

NP_032577.1

NM_008551.1

P49138

44,050 Da

Activated TLR4 Signalling Pathway (575140); B Cell Receptor Signaling Pathway (198285); CREB Phosphorylation Pathway (575126); FAS Pathway And Stress Induction Of HSP Regulation (198421); IL-2 Signaling Pathway (198331); IL-3 Signaling Pathway (198420); IL-6 Signaling Pathway (198302); Immune System Pathway (575095); Innate Immune System Pathway (575115); Leukotriene Synthesis Pathway (574792)

MAPKAPK2: a member of the MAPKAPK family of protein kinases. It is phosphorylated and activated by p38 in response to cytokines, stress and chemotactic factors.MAPKAPK-2 is apparently a direct target of p38 MAPK. HSP27 is one of its in vivo substrates. Two transcript variants encoding two different isoforms have been described. Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); CAMK group; MAPKAPK family; MAPKAPK subfamily. Cellular Component: nucleoplasm; centrosome; cytoplasm; nucleus. Molecular Function: calmodulin-dependent protein kinase activity; nucleotide binding; protein kinase activity; transferase activity; calmodulin binding; protein serine/threonine kinase activity; protein binding; signal transducer activity; calcium-dependent protein serine/threonine kinase activity; transferase activity, transferring phosphorus-containing groups; mitogen-activated protein kinase binding; kinase activity; ATP binding. Biological Process: positive regulation of tumor necrosis factor biosynthetic process; protein amino acid autophosphorylation; cellular response to stress; mRNA stabilization; MAPKKK cascade; response to lipopolysaccharide; protein amino acid phosphorylation; peptidyl-serine phosphorylation; response to cytokine stimulus; regulation of interleukin-6 production; toll-like receptor signaling pathway; response to stress; regulation of tumor necrosis factor production; G2/M transition DNA damage checkpoint; inflammatory response; vascular endothelial growth factor receptor signaling pathway; inner ear development; response to DNA damage stimulus; phosphorylation

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095