catalog number :
MBS9341555
products type :
ELISA Kit
products full name :
Human Protein farnesyltransferase subunit beta, FNTB ELISA Kit
products short name :
[farnesyltransferase, CAAX box, beta]
products name syn :
[Human Protein farnesyltransferase subunit beta (FNTB) ELISA kit; FPTB; MGC31935; ; farnesyltransferase; CAAX box; beta]
other names :
[CHURC1-FNTB protein isoform 2; Protein farnesyltransferase subunit beta; CHURC1-FNTB protein; CHURC1-FNTB readthrough; CAAX farnesyltransferase subunit beta; Ras proteins prenyltransferase subunit beta]
products gene name :
[FNTB]
other gene names :
[CHURC1-FNTB; FNTB; FTase-beta]
uniprot entry name :
FNTB_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FNTB (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_001189487.1
ncbi gb acc num :
NM_001202558.1
ncbi mol weight :
48,774 Da
ncbi pathways :
Terpenoid Backbone Biosynthesis Pathway (83022); Terpenoid Backbone Biosynthesis Pathway (408)
ncbi summary :
This locus represents naturally occurring read-through transcription between the neighboring CHURC1 (churchill domain containing 1) and FNTB (farnesyltransferase, CAAX box, beta) on chromosome 14. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Feb 2011]
uniprot summary :
FNTB: a subunit of farnesyltransferase that is responsible for peptide-binding. Farnesyltransferase catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. Protein type: EC 2.5.1.58; Transferase. Chromosomal Location of Human Ortholog: 14q23.3. Cellular Component: microtubule associated complex; cytosol. Molecular Function: protein binding; farnesyltranstransferase activity; isoprenoid binding; zinc ion binding; drug binding; peptide binding; protein farnesyltransferase activity. Biological Process: rhodopsin mediated signaling; negative regulation of cell proliferation; phototransduction, visible light; protein farnesylation; positive regulation of fibroblast proliferation; regulation of rhodopsin mediated signaling; response to inorganic substance; wound healing; response to cytokine stimulus; positive regulation of cell cycle; response to organic cyclic substance; positive regulation of nitric-oxide synthase biosynthetic process
size4 :
10x96-Strip-Wells