Mouse DNA-binding protein SATB2, SATB2 ELISA Kit | MyBioSource MBS9341509 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse DNA-binding protein SATB2, SATB2 ELISA Kit

catalog :

MBS9341509

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9341509

products type :

ELISA Kit

products full name :

Mouse DNA-binding protein SATB2, SATB2 ELISA Kit

products short name :

[SATB homeobox 2]

products name syn :

[Mouse DNA-binding protein SATB2 (SATB2) ELISA kit; FLJ21474; FLJ32076; KIAA1034; MGC119474; MGC119477; OTTHUMP00000163655; OTTHUMP00000205774; OTTHUMP00000205775; SATB family member 2; two cut domains-containing homeodomain protein; SATB homeobox 2]

other names :

[DNA-binding protein SATB2; DNA-binding protein SATB2; DNA-binding protein SATB2; KIAA1034-like DNA binding protein; special AT-rich sequence-binding protein 2; two cut domains-containing homeodomain protein; special AT-rich sequence binding protein 2; Special AT-rich sequence-binding protein 2]

products gene name :

[SATB2]

other gene names :

[Satb2; Satb2; mKIAA1034; Kiaa1034]

uniprot entry name :

SATB2_MOUSE

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SATB2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

20982839

ncbi acc num :

NP_631885.1

ncbi gb acc num :

NM_139146.2

uniprot acc num :

Q8VI24

ncbi mol weight :

82,559 Da

ncbi pathways :

PluriNetWork Pathway (198307)

uniprot summary :

SATB2: Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper- layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11). Defects in SATB2 are a cause of cleft palate isolated (CPI). A congenital fissure of the soft and/or hard palate, due to faulty fusion. Isolated cleft palate is not associated with cleft lips. Some patients may manifest other craniofacial dysmorphic features, mental retardation, and osteoporosis. A chromosomal aberration involving SATB2 is found in a patient with classical features of Toriello-Carey syndrome. Translocation t(2;14)(q33;q22). Belongs to the CUT homeobox family. Protein type: DNA-binding. Cellular Component: nucleoplasm; transcription factor complex; histone deacetylase complex; nuclear chromatin; cytoplasm; nucleus. Molecular Function: protein binding; DNA binding; sequence-specific DNA binding; chromatin binding. Biological Process: transcription, DNA-dependent; multicellular organismal development; neuron migration; chromatin modification; negative regulation of transcription from RNA polymerase II promoter; palate development; embryonic pattern specification; osteoblast development; embryonic skeletal morphogenesis; chromatin remodeling; regulation of transcription, DNA-dependent; regulation of gene expression; commitment of a neuronal cell to a specific type of neuron in the forebrain; cartilage development; positive regulation of transcription from RNA polymerase II promoter

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095