catalog number :
MBS9341354
products type :
ELISA Kit
products full name :
Human Immunoglobulin lambda-like polypeptide 1, IGLL1 ELISA Kit
products short name :
[immunoglobulin lambda-like polypeptide 1]
products name syn :
[Human Immunoglobulin lambda-like polypeptide 1 (IGLL1) ELISA kit; 14.1; CD179b; IGL1; IGL5; IGLJ14.1; IGLL; IGO; IGVPB; VPREB2; CD179b antigen; Pre-B lymphocyte-specific protein-2; immunoglobulin omega polypeptide chain; immunoglobulin-related 14.1 protein; lambda5; immunoglobulin lambda-like polypeptide 1]
other names :
[immunoglobulin lambda-like polypeptide 1 isoform a; Immunoglobulin lambda-like polypeptide 1; immunoglobulin lambda-like polypeptide 1; lambda5; ig lambda-5; CD179b antigen; CD179 antigen-like family member B; Pre-B lymphocyte-specific protein-2; immunoglobulin-related 14.1 protein; immunoglobulin-related protein 14.1; immunoglobulin omega polypeptide chain; immunoglobulin lambda-like polypeptide 1; CD179 antigen-like family member B; Ig lambda-5; Immunoglobulin omega polypeptide; Immunoglobulin-related protein 14.1; CD_antigen: CD179b]
products gene name :
[IGLL1]
other gene names :
[IGLL1; IGLL1; IGO; 14.1; AGM2; IGL1; IGL5; IGLL; IGVPB; CD179b; VPREB2; IGLJ14.1; IGL1]
uniprot entry name :
IGLL1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 31.2 ng/ml - 1000 ng/ml. Sensitivity: 5.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of IgLL1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_064455.1
ncbi gb acc num :
NM_020070.3
ncbi mol weight :
22,963 Da
ncbi pathways :
Primary Immunodeficiency Pathway (83125); Primary Immunodeficiency Pathway (537)
ncbi summary :
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
IGLL1: Critical for B-cell development. Defects in IGLL1 are the cause of agammaglobulinemia type 2 (AGM2). It is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B-cells due to an early block of B-cell development. Affected individuals develop severe infections in the first years of life. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 22q11.23. Cellular Component: membrane. Biological Process: immune response. Disease: Agammaglobulinemia 2, Autosomal Recessive
size4 :
10x96-Strip-Wells