Canine Hyaluronidase 1, HAase 1 ELISA Kit | MyBioSource MBS9341271 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Canine Hyaluronidase 1, HAase 1 ELISA Kit

catalog :

MBS9341271

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9341271

products type :

ELISA Kit

products full name :

Canine Hyaluronidase 1, HAase 1 ELISA Kit

products short name :

[Hyaluronidase 1 (HAase 1)]

products name syn :

[Canine Hyaluronidase 1 (HAase 1) ELISA Kit; HYAL-1; LUCA1; MGC45987; NAT6; OTTHUMP00000211076; hyaluronidase 1; plasma hyaluronidase; tumor suppressor LUCA-1; Hyaluronidase 1 (HAase 1)]

other names :

[hyaluronidase-1 isoform 1; Hyaluronidase-1; hyaluronidase-1; luCa-1; plasma hyaluronidase; tumor suppressor LUCA-1; lung carcinoma protein 1; hyaluronoglucosaminidase 1; Hyaluronoglucosaminidase-1; Lung carcinoma protein 1; LuCa-1]

products gene name :

[HAase 1]

other gene names :

[HYAL1; HYAL1; NAT6; LUCA1; HYAL-1; LUCA1; Hyal-1; LuCa-1]

uniprot entry name :

HYAL1_HUMAN

reactivity :

Dog

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 6.25ng/ml-200ng/ml. Sensitivity: 1.0ng/ml

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HYAL1 (hereafter termed "analyte") in undiluted original Canine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

24497562

ncbi acc num :

NP_149349.2

ncbi gb acc num :

NM_033159.3

uniprot acc num :

Q12794

ncbi mol weight :

48,368 Da

ncbi pathways :

Chondroitin Sulfate Degradation Pathway (413376); Chondroitin Sulfate Degradation Pathway (468247); Dermatan Sulfate Degradation Pathway (413375); Dermatan Sulfate Degradation Pathway (468240); Glycosaminoglycan Degradation Pathway (82981); Glycosaminoglycan Degradation Pathway (355); Lysosome Pathway (99052); Lysosome Pathway (96865)

ncbi summary :

This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

HYAL1: May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth. Defects in HYAL1 are the cause of mucopolysaccharidosis type 9 (MPS9); also called hyaluronidase deficiency. MPS9 is a lysosomal storage disease characterized by high hyaluronan (HA) concentration in the serum. The clinical features are periarticular soft tissue masses, mild short stature and acetabular erosions, and absence of neurological or visceral involvement. Belongs to the glycosyl hydrolase 56 family. 7 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Glycan Metabolism - glycosaminoglycan degradation; Hydrolase; Secreted, signal peptide; EC 3.2.1.35. Chromosomal Location of Human Ortholog: 3p21.31. Cellular Component: lysosomal lumen; extracellular space; lysosome; cytoplasm; cytoplasmic vesicle. Molecular Function: viral receptor activity; hyaluronan synthase activity; transcription factor binding; hyalurononglucosaminidase activity. Biological Process: positive regulation of cell adhesion; glycosaminoglycan metabolic process; response to virus; pathogenesis; positive regulation of cell growth; hyaluronan catabolic process; chondroitin sulfate metabolic process; response to antibiotic; response to reactive oxygen species; positive regulation of angiogenesis; hyaluronan biosynthetic process; cartilage development; carbohydrate metabolic process; chondroitin sulfate catabolic process; negative regulation of cell growth; inflammatory response; hyaluronan metabolic process; positive regulation of growth; positive regulation of epithelial cell proliferation. Disease: Mucopolysaccharidosis, Type Ix

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095