Mouse Vitamin D3 receptor, VDR ELISA Kit | MyBioSource MBS9340676 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Vitamin D3 receptor, VDR ELISA Kit

catalog :

MBS9340676

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9340676

products type :

ELISA Kit

products full name :

Mouse Vitamin D3 receptor, VDR ELISA Kit

products short name :

vitamin D (1, 25- dihydroxyvitamin D3) receptor

products name syn :

Mouse Vitamin D3 receptor (VDR) ELISA kit; NR1I1; vitamin D (1; 25-dihydroxyvitamin D3) receptor; vitamin D (1; 25- dihydroxyvitamin D3) receptor

other names :

vitamin D3 receptor; Vitamin D3 receptor; vitamin D3 receptor; 1,25-dihydroxyvitamin D3 receptor; nuclear receptor subfamily 1 group I member 1; vitamin D receptor; 1,25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1

products gene name :

VDR

other gene names :

Vdr; Vdr; Nr1i1; Nr1i1; VDR

uniprot entry name :

VDR_MOUSE

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 1.56 nmol/L - 50 nmol/L. Sensitivity: 0.1 nmol/L. Assay Type: Sandwich

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of VDR (hereafter termed this analyte) in undiluted original Mouse serum, plasma and tissue homogenate samples.

ncbi gi num :

31543944

ncbi acc num :

NP_033530.2

ncbi gb acc num :

NM_009504.4

uniprot acc num :

P48281

ncbi mol weight :

47,834 Da

ncbi pathways :

Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213309); Endocrine And Other Factor-regulated Calcium Reabsorption Pathway (213276); Gene Expression Pathway (574654); Generic Transcription Pathway (574655); Mineral Absorption Pathway (212238); Mineral Absorption Pathway (212220); Nuclear Receptor Transcription Pathway (574657); Nuclear Receptors Pathway (198318); Nuclear Receptors In Lipid Metabolism And Toxicity Pathway (198356); Ovarian Infertility Genes Pathway (198410)

uniprot summary :

VDR: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis. Defects in VDR are the cause of rickets vitamin D- dependent type 2A (VDDR2A). A disorder of vitamin D metabolism resulting in severe rickets, hypocalcemia and secondary hyperparathyroidism. Most patients have total alopecia in addition to rickets. Belongs to the nuclear hormone receptor family. NR1 subfamily. Protein type: Transcription factor; Nuclear receptor; DNA-binding. Cellular Component: heterochromatin; nuclear matrix; intracellular membrane-bound organelle; cell; T-tubule; nuclear heterochromatin; caveola; cytosol; nucleoplasm; euchromatin; dense fibrillar component; perinuclear region of cytoplasm; nucleus; receptor complex. Molecular Function: retinoid X receptor binding; vitamin D binding; protein binding; ligand-dependent nuclear receptor activity; DNA binding; zinc ion binding; sequence-specific DNA binding; metal ion binding; steroid hormone receptor activity; vitamin D3 receptor activity; transcription factor activity. Biological Process: lactation; transcription from RNA polymerase II promoter; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; multicellular organismal development; positive regulation of apoptosis involved in mammary gland involution; cell morphogenesis; regulation of calcium ion transport; negative regulation of transcription from RNA polymerase II promoter; intestinal absorption; cellular calcium ion homeostasis; regulation of transcription from RNA polymerase II promoter; negative regulation of cell proliferation; organ morphogenesis; regulation of transcription, DNA-dependent; calcium ion transport; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; skeletal development; positive regulation of keratinocyte differentiation

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage