catalog number :
MBS9340640
products type :
ELISA Kit
products full name :
Human Guanine nucleotide-binding protein subunit alpha-13, GNA13 ELISA Kit
products short name :
guanine nucleotide binding protein (G protein) , alpha 13
products name syn :
Human Guanine nucleotide-binding protein subunit alpha-13 (GNA13) ELISA kit; G13; MGC46138; ; guanine nucleotide binding protein (G protein); alpha 13
other names :
guanine nucleotide-binding protein subunit alpha-13 isoform 2; Guanine nucleotide-binding protein subunit alpha-13; guanine nucleotide-binding protein subunit alpha-13; g alpha-13; G-protein subunit alpha-13; guanine nucleotide binding protein (G protein), alpha 13
products gene name :
GNA13
other gene names :
GNA13; GNA13; G13; G alpha-13; G-protein subunit alpha-13
uniprot entry name :
GNA13_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GNA13 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_001269354.1
ncbi gb acc num :
NM_001282425.1
ncbi mol weight :
44,050 Da
ncbi pathways :
CXCR4-mediated Signaling Events Pathway (137910); G Protein Signaling Pathways (198849); G Alpha (12/13) Signalling Events Pathway (106041); G13 Signaling Pathway (198800); GPCR Downstream Signaling Pathway (119548); Hemostasis Pathway (106028); LPA Receptor Mediated Events Pathway (137928); Long-term Depression Pathway (83086); Long-term Depression Pathway (497); Plasma Membrane Estrogen Receptor Signaling Pathway (138009)
uniprot summary :
G-alpha 13: a guanine nucleotide-binding protein of the G12 class of G-alpha proteins. Activates Rho. Protein kinase A blocks Rho activation by phosphorylation of G-alpha(13). Heterotrimeric G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Regulates cytoplasmic as well as nuclear signaling events such as activation of the Jun N-terminal kinase signaling module, Na+/H+ exchangers, focal adhesion assemblies, and transcriptional activation of specific primary response genes. Protein type: G protein, heterotrimeric; G protein, heterotrimeric alpha G(12); G protein. Chromosomal Location of Human Ortholog: 17q24.3. Cellular Component: focal adhesion; membrane; brush border membrane; plasma membrane; melanosome; heterotrimeric G-protein complex; nucleus. Molecular Function: GTPase activity; signal transducer activity; protein binding; GTP binding; metal ion binding; G-protein beta/gamma-subunit binding; type 1 angiotensin receptor binding; D5 dopamine receptor binding. Biological Process: platelet activation; phospholipase D activation; metabolic process; in utero embryonic development; signal transduction; regulation of cell migration; G-protein signaling, adenylate cyclase activating pathway; Rho protein signal transduction; patterning of blood vessels; regulation of cell shape; elevation of cytosolic calcium ion concentration; cell differentiation; blood coagulation; cell motility