Rat Glutamate [NMDA] receptor subunit epsilon-3, GRIN2C ELISA Kit | MyBioSource MBS9340550 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat Glutamate [NMDA] receptor subunit epsilon-3, GRIN2C ELISA Kit

catalog :

MBS9340550

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9340550

products type :

ELISA Kit

products full name :

Rat Glutamate [NMDA] receptor subunit epsilon-3, GRIN2C ELISA Kit

products short name :

glutamate receptor, ionotropic, N-methyl D-aspartate 2C

products name syn :

Rat Glutamate [NMDA] receptor subunit epsilon-3 (GRIN2C) ELISA kit; NMDAR2C; NR2C; N-methyl-D-aspartate receptor subunit 2C; glutamate receptor; ionotropic; N-methyl D-aspartate 2C

other names :

glutamate receptor ionotropic, NMDA 2C; Glutamate receptor ionotropic, NMDA 2C; glutamate receptor ionotropic, NMDA 2C; NMDAR2C; NMDA glutamate receptor; glutamate receptor, ionotropic, NMDA2C; N-methyl D-aspartate receptor subtype 2C; glutamate [NMDA] receptor subunit epsilon-3; glutamate receptor, ionotropic, N-methyl D-aspartate 2C; Glutamate [NMDA] receptor subunit epsilon-3; N-methyl D-aspartate receptor subtype 2C; NMDAR2C; NR2C

products gene name :

GRIN2C

other gene names :

Grin2c; Grin2c; NR2C; GluN2C; GluN2C; NMDAR2C; NR2C

uniprot entry name :

NMDE3_RAT

reactivity :

Rat

specificity :

No significant cross-reactivity or interference between Rat GRIN2C and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces and Urine. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.

other info2 :

Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated GRIN2C concentrations in Rat serum, plasma and other body fluids. Using Purified Rat GRIN2C antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add GRIN2C and GRIN2C antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of GRIN2C in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated GRIN2C concentrations in Rat serum, plasma and other body fluids. Using Purified Rat GRIN2C antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add GRIN2C and GRIN2C antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of GRIN2C in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

148747563

ncbi acc num :

NP_036707.3

ncbi gb acc num :

NM_012575.3

uniprot acc num :

Q00961

ncbi mol weight :

135,271 Da

ncbi pathways :

Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (574459); Alcoholism Pathway (585585); Alcoholism Pathway (587116); Alzheimer's Disease Pathway (83489); Alzheimer's Disease Pathway (509); Amphetamine Addiction Pathway (547642); Amphetamine Addiction Pathway (550546); Amyotrophic Lateral Sclerosis (ALS) Pathway (83491); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Calcium Signaling Pathway (83442)

ncbi summary :

subunit that in combination with NMDAR1 displays NMDA receptor activity; may contribute to NMDA receptor functional diversity [RGD, Feb 2006]

uniprot summary :

NMDAR2C: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2C/GRIN2C subfamily. Protein type: Membrane protein, integral; Channel, calcium; Channel, ligand-gated; Membrane protein, multi-pass. Cellular Component: postsynaptic membrane; postsynaptic density; dendrite; cell junction; N-methyl-D-aspartate selective glutamate receptor complex. Molecular Function: protein binding; extracellular-glutamate-gated ion channel activity; ionotropic glutamate receptor activity; N-methyl-D-aspartate selective glutamate receptor activity; protein N-terminus binding; cation channel activity; PDZ domain binding. Biological Process: synaptic transmission, glutamatergic; protein localization; regulation of membrane potential; startle response; ionotropic glutamate receptor signaling pathway; directional locomotion; response to wounding; neuromuscular process controlling balance; negative regulation of protein catabolic process; regulation of excitatory postsynaptic membrane potential

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage