product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human MAP kinase-interacting serine/threonine-protein kinase 1, MKNK1 ELISA Kit
catalog :
MBS9340465
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
product information
catalog number :
MBS9340465
products type :
ELISA Kit
products full name :
Human MAP kinase-interacting serine/threonine-protein kinase 1, MKNK1 ELISA Kit
products short name :
[MAP kinase interacting serine/threonine kinase 1]
products name syn :
[Human MAP kinase-interacting serine/threonine-protein kinase 1 (MKNK1) ELISA kit; RP11-49P4.3; MNK1; MAP kinase interacting kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase interacting serine/threonine kinase 1]
other names :
[MAP kinase-interacting serine/threonine-protein kinase 1 isoform 3; MAP kinase-interacting serine/threonine-protein kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAPK signal-integrating kinase 1; Mnk1]
products gene name :
[MKNK1]
other gene names :
[MKNK1; MKNK1; MNK1; MNK1; MAPK signal-integrating kinase 1; Mnk1]
uniprot entry name :
MKNK1_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MKNK1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
207113186
ncbi acc num :
NP_001129025.1
ncbi gb acc num :
NM_001135553.2
uniprot acc num :
Q9BUB5
ncbi mol weight :
51,342 Da
ncbi pathways :
IL-2 Signaling Pathway (198885); Insulin Signaling Pathway (83090); Insulin Signaling Pathway (501); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Negative Regulation Of FGFR Signaling Pathway (477118); Signal Transduction Pathway (477114); Signaling By FGFR Pathway (106343); Signaling Mediated By P38-alpha And P38-beta Pathway (138012); Spry Regulation Of FGF Signaling Pathway (477119)
ncbi summary :
This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]
uniprot summary :
Mnk1: a CAM kinase of the MAPKKAPK family that can regulate translation. Following activation by MAP kinases, Mnk1 phosphorylates eIF4E at Ser209, increasing its affinity for the 7-methylguanosine-containing mRNA cap. Two MAPK phosphorylation sites in mouse Mnk1 (Thr197 and Thr202) are essential for its kinase activity. Three alternatively spliced human isoforms have been described. Protein type: Kinase, protein; Translation; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; CAMK group; MAPKAPK family; MNK subfamily. Chromosomal Location of Human Ortholog: 1p33. Cellular Component: cytosol; nucleus. Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding. Biological Process: peptidyl-serine phosphorylation; fibroblast growth factor receptor signaling pathway; protein amino acid phosphorylation; response to salt stress; regulation of translational initiation
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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