Rat Neuronal acetylcholine receptor subunit alpha-7, CHRNA7 ELISA Kit | MyBioSource MBS9340394 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Rat Neuronal acetylcholine receptor subunit alpha-7, CHRNA7 ELISA Kit

catalog :

MBS9340394

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9340394

products type :

ELISA Kit

products full name :

Rat Neuronal acetylcholine receptor subunit alpha-7, CHRNA7 ELISA Kit

products short name :

cholinergic receptor, nicotinic, alpha 7

products name syn :

Rat Neuronal acetylcholine receptor subunit alpha-7 (CHRNA7) ELISA kit; CHRNA7-2; NACHRA7; a7 nicotinic acetylcholine receptor; alpha 7 neuronal nicotinic acetylcholine receptor; alpha-7 nicotinic cholinergic receptor subunit; cholinergic receptor; nicotinic; alpha polypep; cholinergic receptor; nicotinic; alpha 7

other names :

neuronal acetylcholine receptor subunit alpha-7; Neuronal acetylcholine receptor subunit alpha-7; neuronal acetylcholine receptor subunit alpha-7; bungarotoxin alpha; nicotinic receptor alpha 7 subunit; neuronal nicotinic acetycholine receptor alpha 7; cholinergic receptor, nicotinic, alpha polypeptide 7; C holinergic receptor nicotinic alpha polypeptide 7 (neuronal nicotinic acetycholine receptor alpha 7) (bungarotoxin alpha); C holinergic receptor, nicotinic, alpha polypeptide 7 (neuronal nicotinic acetycholine receptor alpha 7) (bungarotoxin alpha); cholinergic receptor, nicotinic, alpha 7 (neuronal)

products gene name :

CHRNA7

other gene names :

Chrna7; Chrna7; BTX; NARAD; nAChRa7; Acra7

uniprot entry name :

ACHA7_RAT

reactivity :

Rat

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CHRNA7 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

144922602

ncbi acc num :

NP_036964.3

ncbi gb acc num :

NM_012832.3

uniprot acc num :

Q05941

ncbi mol weight :

56,503 Da

ncbi pathways :

Calcium Signaling Pathway (83442); Calcium Signaling Pathway (459); Cholinergic Synapse Pathway (217713); Neuroactive Ligand-receptor Interaction Pathway (83445); Neuroactive Ligand-receptor Interaction Pathway (462); Nicotine Addiction Pathway (583273); Nicotine Addiction Pathway (584676)

ncbi summary :

subunit of nicotinic acetylcholline receptor; may mediate nicotine induced increase in tyrosine hydroxylase expression; may play a role in neuroprotection [RGD, Feb 2006]

uniprot summary :

nAChRA7: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha- 7/CHRNA7 sub-subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Channel, cation; Membrane protein, multi-pass; Channel, ligand-gated. Cellular Component: nicotinic acetylcholine-gated receptor-channel complex; dendrite; postsynaptic density; dendritic spine; lipid raft; presynaptic membrane; asymmetric synapse; postsynaptic membrane; growth cone; cell soma; membrane; axon; cytoplasm; apical plasma membrane; plasma membrane; dendritic shaft; cell junction; external side of plasma membrane. Molecular Function: toxin binding; protein binding; protein homodimerization activity; chloride channel regulator activity; beta-amyloid binding; acetylcholine-gated cation channel activity; acetylcholine receptor activity; drug binding; nicotinic acetylcholine-activated cation-selective channel activity; acetylcholine binding; protein kinase binding; ATPase binding; adenylate cyclase binding. Biological Process: response to nicotine; T cell activation; activation of MAPK activity; generation of action potential; behavioral response to nicotine; behavioral response to ethanol; dopamine biosynthetic process; signal transduction; positive regulation of heart rate in baroreceptor response to decreased systemic arterial blood pressure; synaptic transmission, cholinergic; regulation of synaptic transmission, dopaminergic; ovulation cycle; calcium ion transport; positive regulation of cell proliferation; negative regulation of interleukin-6 production; associative learning; response to food; B cell activation; endocytosis; negative regulation of tumor necrosis factor production; negative regulation of interleukin-1 beta production; regulation of norepinephrine secretion; memory; cellular calcium ion homeostasis; generation of ovulation cycle rhythm; sperm motility; positive regulation of angiogenesis; regulation of membrane potential; response to ethanol; negative regulation of inflammatory response; regulation of inflammatory response; response to hypoxia; ion transport; cognition

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage