catalog number :
MBS9340361
products type :
ELISA Kit
products full name :
Rat Phosphatidylcholine:ceramide cholinephosphotransferase 2, SGMS2 ELISA Kit
products short name :
[sphingomyelin synthase 2]
products name syn :
[Rat Phosphatidylcholine:ceramide cholinephosphotransferase 2 (SGMS2) ELISA kit; MGC26963; SMS2; SM synthase; phosphatidylcholine:ceramide cholinephosphotransferase 2; sphingomyelin synthase 2]
other names :
[phosphatidylcholine:ceramide cholinephosphotransferase 2; Phosphatidylcholine:ceramide cholinephosphotransferase 2; phosphatidylcholine:ceramide cholinephosphotransferase 2; sphingomyelin synthase 2; Sphingomyelin synthase 2]
products gene name :
[SGMS2]
other gene names :
[Sgms2; Sgms2; spermatin; RGD1305778]
uniprot entry name :
SMS2_RAT
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of S-GAG (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001014065.1
ncbi gb acc num :
NM_001014043.1
ncbi mol weight :
42,223 Da
ncbi pathways :
Metabolism Pathway (573935); Metabolism Of Lipids And Lipoproteins Pathway (573950); Sphingolipid De Novo Biosynthesis Pathway (573986); Sphingolipid Metabolism Pathway (83386); Sphingolipid Metabolism Pathway (573985); Sphingolipid Metabolism Pathway (369)
uniprot summary :
Function: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Plasma membrane SMS2 can also convert phosphatidylethanolamine (PE) to ceramide phosphatidylethanolamine (CPE). Major form in liver. Required for cell growth in certain cell types. Regulator of cell surface levels of ceramide, an important mediator of signal transduction and apoptosis. Regulation of sphingomyelin (SM) levels at the cell surface affects insulin sensitivity . Catalytic activity: A ceramide + a phosphatidylcholine = a sphingomyelin + a 1,2-diacyl-sn-glycerol.
size4 :
10x96-Strip-Wells