catalog number :
MBS9340340
products type :
ELISA Kit
products full name :
Rat Proto-oncogene Mas, MAS1 ELISA Kit
products short name :
[MAS1 oncogene]
products name syn :
[Rat Proto-oncogene Mas (MAS1) ELISA kit; MAS; MGC119966; ; MAS1 oncogene]
other names :
[proto-oncogene Mas; Proto-oncogene Mas; proto-oncogene Mas; MAS1 oncogene; MAS proto-oncogene; angiotensin-(1-7) receptor; Mas-related G protein-coupled receptor a; MAS1 proto-oncogene, G protein-coupled receptor]
products gene name :
[MAS1]
other gene names :
[Mas1; Mas1; Mgra; c-mas; Mas; Mas-1]
uniprot entry name :
MAS_RAT
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MAS1 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_036889.1
ncbi gb acc num :
NM_012757.2
ncbi mol weight :
37,131 Da
ncbi pathways :
GPCRs, Class A Rhodopsin-like Pathway (198500); Neuroactive Ligand-receptor Interaction Pathway (83445); Neuroactive Ligand-receptor Interaction Pathway (462); Renin - Angiotensin System Pathway (219775); Renin-angiotensin System Pathway (83467); Renin-angiotensin System Pathway (486)
ncbi summary :
oncogene; may be involved in function or development of neural tissues [RGD, Feb 2006]
uniprot summary :
MAS1: Receptor for angiotensin 1-7. Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Oncoprotein. Cellular Component: cell surface; plasma membrane; integral to membrane. Molecular Function: G-protein coupled receptor activity; peptide hormone binding; peptide binding; angiotensin receptor activity. Biological Process: response to drug; G-protein coupled receptor protein signaling pathway; response to peptide hormone stimulus; negative regulation of protein amino acid phosphorylation; male gonad development; regulation of inflammatory response; positive regulation of cell proliferation; hippocampus development; activation of NF-kappaB-inducing kinase; spermatogenesis; response to activity; positive regulation of DNA replication
size4 :
10x96-Strip-Wells