catalog number :
MBS9340218
products type :
ELISA Kit
products full name :
Human Lipoyltransferase 1, mitochondrial, LIPT1 ELISA Kit
products short name :
[lipoyltransferase 1]
products name syn :
[Human Lipoyltransferase 1; mitochondrial (LIPT1) ELISA kit; MGC12290; MGC13378; lipoate biosynthesis protein; lipoate-protein ligase; lipoyl ligase; lipoyltransferase 1]
other names :
[lipoyltransferase 1, mitochondrial; Lipoyltransferase 1, mitochondrial; lipoyltransferase 1, mitochondrial; lipoyl ligase; lipoate biosynthesis protein; lipoyltransferase 1; Lipoate biosynthesis protein; Lipoate-protein ligase; Lipoyl ligase]
products gene name :
[LIPT1]
other gene names :
[LIPT1; LIPT1]
uniprot entry name :
LIPT_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LIPT1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001191759.1
ncbi gb acc num :
NM_001204830.1
ncbi mol weight :
42,479 Da
ncbi pathways :
Lipoic Acid Metabolism Pathway (83017); Lipoic Acid Metabolism Pathway (403); Lipoate Biosynthesis And Incorporation II Pathway (142210); Lipoate Salvage And Modification Pathway (142211)
ncbi summary :
The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 13. Read-through transcription also exists between this gene and the neighboring downstream mitochondrial ribosomal protein L30 (MRPL30) gene. [provided by RefSeq, Mar 2011]
uniprot summary :
LIPT1: Catalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes. Belongs to the LplA family. Protein type: Transferase; Cofactor and Vitamin Metabolism - lipoic acid; EC 2.3.1.-. Chromosomal Location of Human Ortholog: 2q11.2. Cellular Component: mitochondrion. Molecular Function: transferase activity, transferring acyl groups. Biological Process: protein lipoylation; protein modification process; lipid metabolic process. Disease: Lipoyltransferase 1 Deficiency
size4 :
10x96-Strip-Wells