Human Eukaryotic translation initiation factor 5A-1, EIF5A ELISA Kit | MyBioSource MBS9340205 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Eukaryotic translation initiation factor 5A-1, EIF5A ELISA Kit

catalog :

MBS9340205

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9340205

products type :

ELISA Kit

products full name :

Human Eukaryotic translation initiation factor 5A-1, EIF5A ELISA Kit

products short name :

[eukaryotic translation initiation factor 5A]

products name syn :

[Human Eukaryotic translation initiation factor 5A-1 (EIF5A) ELISA kit; EIF-5A; EIF5A1; MGC104255; MGC99547; eIF5AI; ; eukaryotic translation initiation factor 5A]

other names :

[eukaryotic translation initiation factor 5A-1 isoform A; Eukaryotic translation initiation factor 5A-1; eukaryotic translation initiation factor 5A-1; eIF-4D; eIF-5A1; eIF-5A-1; rev-binding factor; eukaryotic initiation factor 5A; eukaryotic translation initiation factor 5A; Eukaryotic initiation factor 5A isoform 1; eIF-5A; Rev-binding factor; eIF-4D]

products gene name :

[EIF5A]

other gene names :

[EIF5A; EIF5A; EIF-5A; EIF5A1; eIF5AI; eIF-5A-1; eIF-5A1; eIF-5A]

uniprot entry name :

IF5A1_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of EIF5A1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

219555707

ncbi acc num :

NP_001137232.1

ncbi gb acc num :

NM_001143760.1

uniprot acc num :

P63241

ncbi mol weight :

16,832 Da

ncbi pathways :

Hypusine Synthesis From EIF5A-lysine Pathway (106240); Metabolism Of Proteins Pathway (106230); PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway (106231); Post-translational Protein Modification Pathway (161012); Translation Factors Pathway (198803)

uniprot summary :

EIF5A: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF- alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts. Belongs to the eIF-5A family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Translation; Translation initiation. Chromosomal Location of Human Ortholog: 17p13-p12. Cellular Component: endoplasmic reticulum membrane; membrane; cytoplasm; nuclear pore; nucleus; cytosol; annulate lamellae. Molecular Function: protein binding; RNA binding; ribosome binding; protein N-terminus binding; translation elongation factor activity; U6 snRNA binding. Biological Process: mRNA export from nucleus; cellular protein metabolic process; translational frameshifting; apoptosis; positive regulation of cell proliferation; positive regulation of translational elongation; hypusine biosynthetic process from peptidyl-lysine; nucleocytoplasmic transport; protein export from nucleus; post-translational protein modification; positive regulation of translational termination

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage