catalog number :
MBS9339758
products type :
ELISA Kit
products full name :
Human Keratin, type II cuticular Hb1, KRT81 ELISA Kit
products short name :
[keratin 81]
products name syn :
[Human Keratin; type II cuticular Hb1 (KRT81) ELISA kit; HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1; hard keratin; type II; 1; keratin; hair; basic; 1; keratin 81]
other names :
[keratin, type II cuticular Hb1; Keratin, type II cuticular Hb1; keratin, type II cuticular Hb1; K81; ghHb1; MLN 137; keratin-81; hair keratin K2.9; type-II keratin Kb21; keratin, hair, basic, 1; hard keratin, type II, 1; type II hair keratin Hb1; metastatic lymph node 137 gene protein; keratin 81; Hair keratin K2.9; Keratin, hair, basic, 1; Keratin-81; K81; Metastatic lymph node 137 gene protein; MLN 137; Type II hair keratin Hb1; Type-II keratin Kb21; ghHKb1; ghHb1]
products gene name :
[KRT81]
other gene names :
[KRT81; KRT81; HB1; Hb-1; KRTHB1; MLN137; ghHkb1; hHAKB2-1; KRTHB1; MLN137; K81; MLN 137; ghHb1]
uniprot entry name :
KRT81_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KRT81 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_002272.2
ncbi gb acc num :
NM_002281.3
ncbi mol weight :
54,928 Da
ncbi summary :
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008]
uniprot summary :
K81: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: extracellular space; keratin filament. Molecular Function: protein binding; structural molecule activity. Disease: Monilethrix
size4 :
10x96-Strip-Wells