Human Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, FNTA ELISA Kit | MyBioSource MBS9339744 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, FNTA ELISA Kit

catalog :

MBS9339744

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9339744

products type :

ELISA Kit

products full name :

Human Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, FNTA ELISA Kit

products short name :

farnesyltransferase, CAAX box, alpha

products name syn :

Human Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) ELISA kit; FPTA; MGC99680; PGGT1A; PTAR2; FTase-alpha; GGTase-I-alpha; farnesyltransferase alpha-subunit; protein prenyltransferase alpha subunit repeat containing 2; ras proteins prenyltransferase alpha; type I pr; farnesyltransferase; CAAX box; alpha

other names :

protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; FTase-alpha; GGTase-I-alpha; farnesyl-protein transferase alpha-subunit; ras proteins prenyltransferase subunit alpha; type I protein geranyl-geranyltransferase alpha subunit; protein prenyltransferase alpha subunit repeat containing 2; farnesyltransferase, CAAX box, alpha; CAAX farnesyltransferase subunit alpha; FTase-alpha; Ras proteins prenyltransferase subunit alpha; Type I protein geranyl-geranyltransferase subunit alpha; GGTase-I-alpha

products gene name :

FNTA

other gene names :

FNTA; FNTA; FPTA; PTAR2; PGGT1A; GGTase-I-alpha

uniprot entry name :

FNTA_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FNTA (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

ncbi gi num :

4503771

ncbi acc num :

NP_002018.1

ncbi gb acc num :

NM_002027.2

uniprot acc num :

P49354

ncbi mol weight :

44,409 Da

ncbi pathways :

Apoptosis Pathway (105648); Apoptotic Cleavage Of Cellular Proteins Pathway (105678); Apoptotic Execution Phase Pathway (105677); TGF-beta Receptor Signaling Pathway (198774); Terpenoid Backbone Biosynthesis Pathway (83022); Terpenoid Backbone Biosynthesis Pathway (408)

ncbi summary :

Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]

uniprot summary :

FNTA: Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK. Belongs to the protein prenyltransferase subunit alpha family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.5.1.59; Transferase; EC 2.5.1.58. Chromosomal Location of Human Ortholog: 8p11. Cellular Component: microtubule associated complex; cytoplasm; cytosol. Molecular Function: protein binding; protein geranylgeranyltransferase activity; CAAX-protein geranylgeranyltransferase activity; microtubule binding; acetylcholine receptor regulator activity; receptor tyrosine kinase binding; alpha-tubulin binding; protein farnesyltransferase activity; Rab-protein geranylgeranyltransferase activity. Biological Process: rhodopsin mediated signaling; protein geranylgeranylation; phototransduction, visible light; protein farnesylation; regulation of rhodopsin mediated signaling; neurotransmitter receptor metabolic process; apoptosis; transforming growth factor beta receptor signaling pathway; regulation of receptor activity; cell structure disassembly during apoptosis

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage