product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Vitamin D 25-hydroxylase, CYP2R1 ELISA Kit
catalog :
MBS9339482
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9339482
products type :
ELISA Kit
products full name :
Mouse Vitamin D 25-hydroxylase, CYP2R1 ELISA Kit
products short name :
cytochrome P450, family 2, subfamily R, polypeptide 1
products name syn :
Mouse Vitamin D 25-hydroxylase (CYP2R1) ELISA kit; MGC4663; cytochrome P450; family 2; R1; vitamin D 25-hydroxylase; cytochrome P450; family 2; subfamily R; polypeptide 1
other names :
vitamin D 25-hydroxylase; Vitamin D 25-hydroxylase; vitamin D 25-hydroxylase; cytochrome P450, 2r1; cytochrome P450, family 2, subfamily r, polypeptide 1; Cytochrome P450 2R1
products gene name :
CYP2R1
other gene names :
Cyp2r1; Cyp2r1
uniprot entry name :
CP2R1_MOUSE
reactivity :
Mouse
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CYP2R1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
34330188
ncbi acc num :
NP_796356.2
ncbi gb acc num :
NM_177382.4
uniprot acc num :
Q6VVW9
ncbi mol weight :
57,313 Da
ncbi pathways :
Biological Oxidations Pathway (574888); Cholecalciferol Biosynthesis Pathway (421791); Cholecalciferol Biosynthesis Pathway (468294); Cytochrome P450 - Arranged By Substrate Type Pathway (574890); Metabolism Pathway (574739); Metabolism Of Lipids And Lipoproteins Pathway (574754); Metabolism Of Steroid Hormones And Vitamins A And D Pathway (574800); Phase 1 - Functionalization Of Compounds Pathway (574889); Steroid Biosynthesis Pathway (83137); Steroid Biosynthesis Pathway (298)
uniprot summary :
CYP2R1: Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D(2) and D(3). Defects in CYP2R1 are the cause of rickets vitamin D- dependent type 1B (VDDR1B); also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. A disorder caused by a selective deficiency of the active form of vitamin D (1,25-dihydroxyvitamin D3) and resulting in defective bone mineralization and clinical features of rickets. The patients sera have low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activityand low levels of 25-hydroxyvitamin D. Belongs to the cytochrome P450 family. Protein type: Oxidoreductase; EC 1.14.13.15. Cellular Component: membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm. Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; cholestanetriol 26-monooxygenase activity; metal ion binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; steroid hydroxylase activity; oxidoreductase activity; oxygen binding; monooxygenase activity; vitamin D3 25-hydroxylase activity. Biological Process: organic acid metabolic process; xenobiotic metabolic process; exogenous drug catabolic process; vitamin D metabolic process
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

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