Human Very long-chain acyl-CoA synthetase, SLC27A2 ELISA Kit | MyBioSource MBS9339225 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Very long-chain acyl-CoA synthetase, SLC27A2 ELISA Kit

catalog :

MBS9339225

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9339225

products type :

ELISA Kit

products full name :

Human Very long-chain acyl-CoA synthetase, SLC27A2 ELISA Kit

products short name :

[solute carrier family 27 (fatty acid transporter) , member 2]

products name syn :

[Human Very long-chain acyl-CoA synthetase (SLC27A2) ELISA kit; ACSVL1; FACVL1; FATP2; HsT17226; VLACS; VLCS; hFACVL1; fatty acid transport protein 2; very long-chain fatty-acid-coenzyme A ligase 1; very-long-chain acyl-CoA synthetase; solute carrier family 27 (fatty acid transporter); member 2]

other names :

[very long-chain acyl-CoA synthetase isoform 2; Very long-chain acyl-CoA synthetase; very long-chain acyl-CoA synthetase; FATP-2; THCA-CoA ligase; fatty acid transport protein 2; long-chain-fatty-acid--CoA ligase; solute carrier family 27 member 2; very-long-chain acyl-CoA synthetase; very long-chain-fatty-acid-CoA ligase; very long-chain fatty-acid-coenzyme A ligase 1; fatty-acid-coenzyme A ligase, very long-chain 1; solute carrier family 27 (fatty acid transporter), member 2; Fatty acid transport protein 2; FATP-2; Fatty-acid-coenzyme A ligase, very long-chain 1; Long-chain-fatty-acid--CoA ligase (EC:6.2.1.3); Solute carrier family 27 member 2; THCA-CoA ligase; Very long-chain-fatty-acid-CoA ligase]

products gene name :

[SLC27A2]

other gene names :

[SLC27A2; SLC27A2; VLCS; FATP2; VLACS; ACSVL1; FACVL1; hFACVL1; HsT17226; ACSVL1; FACVL1; FATP2; VLACS; VLACS; VLCS; FATP-2]

uniprot entry name :

S27A2_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml

other info2 :

Intra-assay Precision: Intra-assay CV(%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SLC27A2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

227499621

ncbi acc num :

NP_001153101.1

ncbi gb acc num :

NM_001159629.1

uniprot acc num :

O14975

ncbi mol weight :

70,312 Da

ncbi pathways :

Alpha-oxidation Of Phytanate Pathway (106137); Bile Acid And Bile Salt Metabolism Pathway (106144); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); Peroxisomal Lipid Metabolism Pathway (106136); Peroxisome Pathway (131226); Peroxisome Pathway (131126); Synthesis Of Bile Acids And Bile Salts Pathway (106145)

ncbi summary :

The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

uniprot summary :

SLC27A2: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes. Belongs to the ATP-dependent AMP-binding enzyme family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Ligase; Membrane protein, integral; Membrane protein, multi-pass; EC 6.2.1.3. Chromosomal Location of Human Ortholog: 15q21.2. Cellular Component: peroxisomal membrane; endoplasmic reticulum membrane; integral to peroxisomal membrane; mitochondrion; endoplasmic reticulum lumen; integral to endoplasmic reticulum membrane. Molecular Function: enzyme binding; fatty acid transporter activity; very-long-chain-fatty-acid-CoA ligase activity; phytanate-CoA ligase activity; ATP binding; receptor binding; long-chain-fatty-acid-CoA ligase activity. Biological Process: bile acid biosynthetic process; fatty acid beta-oxidation; bile acid metabolic process; very-long-chain fatty acid catabolic process; cellular lipid metabolic process; long-chain fatty acid metabolic process; fatty acid alpha-oxidation

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage