Mouse Gamma-aminobutyric acid receptor subunit alpha-1, GABRA1 ELISA Kit | MyBioSource MBS9339158 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Gamma-aminobutyric acid receptor subunit alpha-1, GABRA1 ELISA Kit

catalog :

MBS9339158

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9339158

products type :

ELISA Kit

products full name :

Mouse Gamma-aminobutyric acid receptor subunit alpha-1, GABRA1 ELISA Kit

products short name :

gamma-aminobutyric acid (GABA) A receptor, alpha 1

products name syn :

Mouse Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1) ELISA kit; ECA4; EJM; EJM5; ; gamma-aminobutyric acid (GABA) A receptor; alpha 1

other names :

gamma-aminobutyric acid receptor subunit alpha-1; Gamma-aminobutyric acid receptor subunit alpha-1; gamma-aminobutyric acid receptor subunit alpha-1; GABAA alpha 1; GABAAR alpha1; GABA(A) receptor subunit alpha-1; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 1; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1; GABA(A) receptor subunit alpha-1

products gene name :

GABRA1

other gene names :

Gabra1; Gabra1; Gabra-1; Gabra-1

uniprot entry name :

GBRA1_MOUSE

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between Mouse GABRA1 and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces and Urine. Assay Type: Sandwich. Detection Range: 0.5mumol/L-16mumol/L. Sensitivity: 0.1mumol/L.

other info2 :

Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated GABRA1 concentrations in Human serum, plasma and other body fluids. Using Purified Human GABRA1 antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add GABRA1 and GABRA1 antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of GABRA1 in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intray-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated GABRA1 concentrations in Human serum, plasma and other body fluids. Using Purified Human GABRA1 antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add GABRA1 and GABRA1 antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of GABRA1 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

6753936

ncbi acc num :

NP_034380.1

ncbi gb acc num :

NM_010250.5

uniprot acc num :

P62812

ncbi mol weight :

51,754 Da

ncbi pathways :

GABAergic Synapse Pathway (377269); GABAergic Synapse Pathway (377129); Morphine Addiction Pathway (552689); Morphine Addiction Pathway (554808); Neuroactive Ligand-receptor Interaction Pathway (83250); Neuroactive Ligand-receptor Interaction Pathway (462); Nicotine Addiction Pathway (583269); Nicotine Addiction Pathway (584676); Retrograde Endocannabinoid Signaling Pathway (537783); Retrograde Endocannabinoid Signaling Pathway (539806)

uniprot summary :

GABRA1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Defects in GABRA1 are the cause of childhood absence epilepsy type 4 (ECA4). A subtype of idiopathic generalized epilepsy characterized by onset at age 6-7 years, frequent absence seizures (several per day) and bilateral, synchronous, symmetric 3-Hz spike waves on EEG. During adolescence, tonic-clonic and myoclonic seizures may develop. Absence seizures may either remit or persist into adulthood. Defects in GABRA1 are the cause of juvenile myoclonic epilepsy type 5 (EJM5). A subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily. Protein type: Transporter; Transporter, ion channel; Membrane protein, multi-pass; Membrane protein, integral; Channel, ligand-gated. Cellular Component: postsynaptic membrane; membrane; integral to plasma membrane; integral to membrane; plasma membrane; synapse; cell junction. Molecular Function: chloride channel activity; protein binding; GABA-A receptor activity; GABA receptor activity; ion channel activity; drug binding; extracellular ligand-gated ion channel activity. Biological Process: transport; synaptic transmission, GABAergic; ion transport; chloride transport; gamma-aminobutyric acid signaling pathway

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage