product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Mouse Poly (A) RNA polymerase, mitochondrial, MTPAP ELISA Kit
catalog :
MBS9339008
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9339008
products type :
ELISA Kit
products full name :
Mouse Poly (A) RNA polymerase, mitochondrial, MTPAP ELISA Kit
products short name :
mitochondrial poly (A) polymerase
products name syn :
Mouse Poly (A) RNA polymerase; mitochondrial (MTPAP) ELISA kit; FLJ10486; PAPD1; RP11-305E6.3; PAP associated domain containing 1; mitochondrial poly (A) polymerase
other names :
poly(A) RNA polymerase, mitochondrial; Poly(A) RNA polymerase, mitochondrial; poly(A) RNA polymerase, mitochondrial; poly(A) RNA polymerase, mitochondrial; PAP associated domain containing 1; polynucleotide adenylyltransferase; PAP-associated domain-containing protein 1; mitochondrial poly(A) polymerase; PAP-associated domain-containing protein 1; Polynucleotide adenylyltransferase
products gene name :
MTPAP
other gene names :
Mtpap; Mtpap; Papd1; AW551379; 0610027A18Rik; Papd1; PAP
uniprot entry name :
PAPD1_MOUSE
reactivity :
Mouse
storage stability :
Store all reagents at 2-8 degree C
ncbi gi num :
21312970
ncbi acc num :
NP_080433.1
ncbi gb acc num :
NM_026157.2
uniprot acc num :
Q9D0D3
ncbi mol weight :
65,229 Da
uniprot summary :
PAPD1: Polymerase that creates the 3 poly(A) tail of mitochondrial transcripts. Can use all four nucleotides, but has higher activity with ATP and UTP (in vitro). Plays a role in replication-dependent histone mRNA degradation. May be involved in the terminal uridylation of mature histone mRNAs before their degradation is initiated. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA. Defects in MTPAP are the cause of spastic ataxia autosomal recessive type 4 (SPAX4). A slowly progressive neurodegenerative disease characterized by cerebellar ataxia, spastic paraparesis, dysarthria, and optic atrophy. Affected individuals exhibit a drastic decrease in poly(A) tail length of representative mitochondrial mRNA transcripts, including COX1 and RNA14 (PubMed:20970105). Belongs to the DNA polymerase type-B-like family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Transferase; EC 2.7.7.19; RNA processing. Cellular Component: intracellular membrane-bound organelle; mitochondrion; cytoplasm. Molecular Function: transferase activity; identical protein binding; polynucleotide adenylyltransferase activity; protein homodimerization activity; RNA binding; metal ion binding; manganese ion binding; nucleotide binding; magnesium ion binding; ATP binding. Biological Process: transcription, DNA-dependent; mRNA polyadenylation; mRNA processing
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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