Human Mucosa-associated lymphoid tissue lymphoma transloCation protein 1, MALT1 ELISA Kit | MyBioSource MBS9338753 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Mucosa-associated lymphoid tissue lymphoma transloCation protein 1, MALT1 ELISA Kit

catalog :

MBS9338753

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9338753

products type :

ELISA Kit

products full name :

Human Mucosa-associated lymphoid tissue lymphoma transloCation protein 1, MALT1 ELISA Kit

products short name :

mucosa associated lymphoid tissue lymphoma translocation gene 1

products name syn :

Human Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) ELISA kit; DKFZp434L132; MLT; MLT1; MALT associated translocation; MALT-lymphoma associated translocation; caspase-like protein; mucosa associated lymphoid tissue lymphoma translocation protein 1; paracaspase; mucosa associated lymphoid tissue lymphoma translocation gene 1

other names :

mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform a; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; mucosa-associated lymphoid tissue lymphoma translocation protein 1; paracaspase; caspase-like protein; MALT lymphoma-associated translocation; mucosa associated lymphoid tissue lymphoma translocation gene 1; MALT lymphoma-associated translocation; Paracaspase

products gene name :

MALT1

other gene names :

MALT1; MALT1; MLT; MLT1; IMD12; MLT

uniprot entry name :

MALT1_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MALT1 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

ncbi gi num :

5803078

ncbi acc num :

NP_006776.1

ncbi gb acc num :

NM_006785.3

uniprot acc num :

Q9UDY8

ncbi mol weight :

92,272 Da

ncbi pathways :

Activation Of NF-kappaB In B Cells Pathway (576251); Adaptive Immune System Pathway (366160); B Cell Receptor Signaling Pathway (83081); B Cell Receptor Signaling Pathway (492); BCR Signaling Pathway (138058); Canonical NF-kappaB Pathway (138030); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream TCR Signaling Pathway (106418); Immune System Pathway (106386); NF-kappa B Signaling Pathway (634527)

ncbi summary :

This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

MALT1: Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. Binds through its Ig-like domains to BCL10. Forms oligomers which bind to TRAF6. Highly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung. Belongs to the peptidase C14B family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Nuclear export; Apoptosis; EC 3.4.22.-; Protease; Ligase; Ubiquitin conjugating system; Adaptor/scaffold. Chromosomal Location of Human Ortholog: 18q21. Cellular Component: CBM complex; protein complex; perinuclear region of cytoplasm; cytoplasm; plasma membrane; nucleolus; nucleus; cytosol. Molecular Function: peptidase activity; protein binding; signal transducer activity; protease binding; protein self-association; cysteine-type endopeptidase activity; kinase activator activity; ubiquitin-protein ligase activity. Biological Process: response to fungus; positive regulation of I-kappaB kinase/NF-kappaB cascade; nuclear export; activation of NF-kappaB-inducing kinase; protein ubiquitination; positive regulation of T cell cytokine production; defense response; proteolysis; T cell receptor signaling pathway; protein oligomerization; activation of NF-kappaB transcription factor; regulation of apoptosis; T cell proliferation; B-1 B cell differentiation; positive regulation of protein ubiquitination; regulation of T cell receptor signaling pathway; response to molecule of bacterial origin; positive regulation of interleukin-2 production; innate immune response; positive regulation of T cell activation; negative regulation of apoptosis. Disease: Immunodeficiency 12

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage