Human Transient receptor potential Cation channel subfamily M member 2, TRPM2 ELISA Kit | MyBioSource MBS9338289 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Transient receptor potential Cation channel subfamily M member 2, TRPM2 ELISA Kit

catalog :

MBS9338289

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9338289

products type :

ELISA Kit

products full name :

Human Transient receptor potential Cation channel subfamily M member 2, TRPM2 ELISA Kit

products short name :

[transient receptor potential cation channel, subfamily M, member 2]

products name syn :

[Human Transient receptor potential cation channel subfamily M member 2 (TRPM2) ELISA kit; EREG1; KNP3; LTRPC2; MGC133383; NUDT9H; NUDT9L1; TRPC7; OTTHUMP00000109530; estrogen responsive element associated gene 1; long transient receptor potential channel 2; transient receptor potential chan; transient receptor potential cation channel; subfamily M; member 2]

other names :

[transient receptor potential cation channel subfamily M member 2; Transient receptor potential cation channel subfamily M member 2; transient receptor potential cation channel subfamily M member 2; LTrpC-2; transient receptor potential channel 7; long transient receptor potential channel 2; estrogen-responsive element-associated gene 1 protein; transient receptor potential cation channel, subfamily M, member 2; Estrogen-responsive element-associated gene 1 protein; Long transient receptor potential channel 2; LTrpC-2; LTrpC2; Transient receptor potential channel 7; TrpC7]

products gene name :

[TRPM2]

other gene names :

[TRPM2; TRPM2; KNP3; EREG1; TRPC7; LTRPC2; NUDT9H; NUDT9L1; EREG1; KNP3; LTRPC2; TRPC7; LTrpC-2; LTrpC2; TrpC7]

uniprot entry name :

TRPM2_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 15.6 mug/ml - 500 mug/ml. Sensitivity: 2.0 mug/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TRPM2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

4507689

ncbi acc num :

NP_003298.1

ncbi gb acc num :

NM_003307.3

uniprot acc num :

O94759

ncbi mol weight :

171,198 Da

ncbi summary :

The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

uniprot summary :

TRPM2: Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity. Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Transporter; Hydrolase; Channel, calcium; Membrane protein, integral; EC 3.6.1.13. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: ADP-ribose diphosphatase activity; calcium channel activity; sodium channel activity; manganese ion transmembrane transporter activity. Biological Process: response to hydroperoxide; metabolic process; calcium ion transport; transmembrane transport

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage