Human TATA box-binding protein-associated factor RNA polymerase I subunit C, TAF1C ELISA Kit | MyBioSource MBS9338241 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human TATA box-binding protein-associated factor RNA polymerase I subunit C, TAF1C ELISA Kit

catalog :

MBS9338241

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9338241

products type :

ELISA Kit

products full name :

Human TATA box-binding protein-associated factor RNA polymerase I subunit C, TAF1C ELISA Kit

products short name :

[TATA box binding protein (TBP) -associated factor, RNA polymerase I, C, 110kDa]

products name syn :

[Human TATA box-binding protein-associated factor RNA polymerase I subunit C (TAF1C) ELISA kit; MGC:39976; SL1; TAFI110; TAFI95; SL1; 110kD subunit; TBP-associated factor 1C; transcription factor SL1; TATA box binding protein (TBP) -associated factor; RNA polymerase I; C; 110kDa]

other names :

[TATA box-binding protein-associated factor RNA polymerase I subunit C isoform 3; TATA box-binding protein-associated factor RNA polymerase I subunit C; TATA box-binding protein-associated factor RNA polymerase I subunit C; SL1, 110kD subunit; TBP-associated factor 1C; transcription factor SL1; TATA box-binding protein-associated factor 1C; transcription initiation factor SL1/TIF-IB subunit C; RNA polymerase I-specific TBP-associated factor 110 kDa; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; RNA polymerase I-specific TBP-associated factor 110 kDa; TAFI110; TATA box-binding protein-associated factor 1C; TBP-associated factor 1C; Transcription initiation factor SL1/TIF-IB subunit C]

products gene name :

[TAF1C]

other gene names :

[TAF1C; TAF1C; SL1; TAFI95; TAFI110; MGC:39976; TAFI110; TBP-associated factor 1C]

uniprot entry name :

TAF1C_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TAF1C (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

341926281

ncbi acc num :

NP_001230085.1

ncbi gb acc num :

NM_001243156.1

uniprot acc num :

Q15572

ncbi mol weight :

95,213 Da

ncbi pathways :

Gene Expression Pathway (105937); RNA Polymerase I Chain Elongation Pathway (106555); RNA Polymerase I Promoter Clearance Pathway (106551); RNA Polymerase I Promoter Escape Pathway (106554); RNA Polymerase I Transcription Pathway (106550); RNA Polymerase I Transcription Initiation Pathway (106553); RNA Polymerase I Transcription Termination Pathway (106556); RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway (160948)

ncbi summary :

Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]

uniprot summary :

TAF1C: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription initiation complex. Chromosomal Location of Human Ortholog: 16q24. Cellular Component: nucleoplasm. Molecular Function: protein binding; DNA binding. Biological Process: transcription from RNA polymerase II promoter; chromatin silencing at rDNA; negative regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; gene expression; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter; regulation of gene expression, epigenetic

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage