catalog number :
MBS9338214
products type :
ELISA Kit
products full name :
Mouse Endoplasmic reticulum aminopeptidase 1, ERAP1 ELISA Kit
products short name :
[endoplasmic reticulum aminopeptidase 1]
products name syn :
[Mouse Endoplasmic reticulum aminopeptidase 1 (ERAP1) ELISA kit; A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; KIAA0525; PILS-AP; PILSAP; adipocyte-derived leucine aminopeptidase; aminopeptidase PILS; aminopeptidase regulator of TNFR1 shedding; puromycin-insens; endoplasmic reticulum aminopeptidase 1]
other names :
[endoplasmic reticulum aminopeptidase 1; Endoplasmic reticulum aminopeptidase 1; endoplasmic reticulum aminopeptidase 1; A-LAP; ARTS-1; PILS-AP; aminopeptidase PILS; VEGF-induced aminopeptidase; adipocyte-derived leucine aminopeptidase; puromycin-insensitive leucyl-specific aminopeptidase; type 1 tumor necrosis factor receptor shedding aminopeptidase regulator; endoplasmic reticulum aminopeptidase 1; ARTS-1; Adipocyte-derived leucine aminopeptidase; A-LAP; Aminopeptidase PILS; Puromycin-insensitive leucyl-specific aminopeptidase; PILS-AP; VEGF-induced aminopeptidase]
products gene name :
[ERAP1]
other gene names :
[Erap1; Erap1; Arts1; ERAAP; PILSA; PILSAP; Appils; Arts1; A-LAP; PILS-AP]
uniprot entry name :
ERAP1_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ERAP1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_109636.1
ncbi gb acc num :
NM_030711.4
ncbi mol weight :
106,599 Da
ncbi pathways :
Adaptive Immune System Pathway (640102); Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway (640120); Class I MHC Mediated Antigen Processing Presentation Pathway (640118); Immune System Pathway (640101)
uniprot summary :
ARTS1: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney. Belongs to the peptidase M1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Protease; EC 3.4.11.-. Cellular Component: extracellular space; intracellular membrane-bound organelle; membrane; endoplasmic reticulum lumen; endoplasmic reticulum; cytoplasm; extracellular region; integral to membrane. Molecular Function: peptidase activity; interleukin-6 receptor binding; metalloexopeptidase activity; metallopeptidase activity; hydrolase activity; zinc ion binding; metal ion binding; aminopeptidase activity; tumor necrosis factor receptor binding. Biological Process: positive regulation of angiogenesis; immune system process; membrane protein ectodomain proteolysis; proteolysis
size4 :
10x96-Strip-Wells