catalog number :
MBS9337822
products type :
ELISA Kit
products full name :
Human NACHT, LRR and PYD domains-containing protein 7, NLRP7 ELISA Kit
products short name :
[NLR family, pyrin domain containing 7]
products name syn :
[Human NACHT; LRR and PYD domains-containing protein 7 (NLRP7) ELISA kit; CLR19.4; FLJ94610; HYDM; MGC126470; MGC126471; NALP7; NOD12; PAN7; PYPAF3; NACHT; LRR and PYD containing protein 7; NACHT; leucine rich repeat and PYD containing 7; PYRIN-containing Apaf1-like protein; NLR family; pyrin domain containing 7]
other names :
[NACHT, LRR and PYD domains-containing protein 7 isoform 3; NACHT, LRR and PYD domains-containing protein 7; NACHT, LRR and PYD domains-containing protein 7; PYRIN-containing Apaf1-like protein 3; NACHT, LRR and PYD containing protein 7; NACHT, leucine rich repeat and PYD containing 7; nucleotide-binding oligomerization domain protein 12; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7; NLR family, pyrin domain containing 7; Nucleotide-binding oligomerization domain protein 12; PYRIN-containing APAF1-like protein 3]
products gene name :
[NLRP7]
other gene names :
[NLRP7; NLRP7; HYDM; PAN7; NALP7; NOD12; PYPAF3; CLR19.4; NALP7; NOD12; PYPAF3]
uniprot entry name :
NALP7_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of NLRP4 (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001120727.1
ncbi gb acc num :
NM_001127255.1
ncbi mol weight :
111,807 Da
ncbi summary :
This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
NLRP7: Inhibits CASP1/caspase-1-dependent IL1B secretion. Defects in NLRP7 are the cause of hydatidiform mole recurrent type 1 (HYDM1). A disorder characterized by excessive trophoblast development and the presence of a growing mass of tissue inside the uterus at the beginning of a pregnancy. It leads to abnormal pregnancies with no embryo, and cystic degeneration of the chorionic villi. Belongs to the NLRP family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Apoptosis. Chromosomal Location of Human Ortholog: 19q13.42. Molecular Function: ATP binding. Disease: Hydatidiform Mole, Recurrent, 1
size4 :
10x96-Strip-Wells