catalog number :
MBS9337732
products type :
ELISA Kit
products full name :
Mouse Neuroepithelial cell-transforming gene 1 protein, NET1 ELISA Kit
products short name :
[neuroepithelial cell transforming 1]
products name syn :
[Mouse Neuroepithelial cell-transforming gene 1 protein (NET1) ELISA kit; RP11-116G8.1; ARHGEF8; NET1A; Rho guanine nucleotide exchange factor (GEF) 8; guanine nucleotide regulatory protein (oncogene) ; neuroepithelial cell transforming gene 1; neuroepithelioma transforming g; neuroepithelial cell transforming 1]
other names :
[neuroepithelial cell-transforming gene 1 protein isoform 2; Neuroepithelial cell-transforming gene 1 protein; neuroepithelial cell-transforming gene 1 protein; Net1 homolog; rho guanine nucleotide exchange factor 8; guanine nucleotide regulatory protein (oncogene); neuroepithelial cell transforming gene 1; Rho guanine nucleotide exchange factor 8]
products gene name :
[NET1]
other gene names :
[Net1; Net1; Net1a; mNET1; Arhgef8]
uniprot entry name :
ARHG8_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NET1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001040624.1
ncbi gb acc num :
NM_001047159.2
ncbi mol weight :
67,734 Da
ncbi pathways :
Cell Death Signalling Via NRAGE, NRIF And NADE Pathway (575365); G Alpha (12/13) Signalling Events Pathway (575459); GPCR Downstream Signaling Pathway (575452); NRAGE Signals Death Through JNK Pathway (575366); Rho GTPase Cycle Pathway (575412); Signal Transduction Pathway (575318); Signaling By GPCR Pathway (575424); Signaling By Rho GTPases Pathway (575411); Signalling By NGF Pathway (575361); P75 NTR Receptor-mediated Signalling Pathway (575363)
uniprot summary :
NET1: Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; GEFs; GEFs, Rac/Rho; Oncoprotein. Cellular Component: cytoplasm; plasma membrane; nucleus. Molecular Function: Rho guanyl-nucleotide exchange factor activity; protein binding; guanyl-nucleotide exchange factor activity; GTP-Rho binding. Biological Process: positive regulation of apoptosis; myoblast migration; regulation of Rho protein signal transduction
size4 :
10x96-Strip-Wells