catalog number :
MBS9337565
products type :
ELISA Kit
products full name :
Rat Vitamin K-dependent gamma-carboxylase, GGCX ELISA Kit
products short name :
gamma-glutamyl carboxylase
products name syn :
Rat Vitamin K-dependent gamma-carboxylase (GGCX) ELISA kit; FLJ26629; VKCFD1; vitamin K-dependent gamma-carboxylase; gamma-glutamyl carboxylase
other names :
vitamin K-dependent gamma-carboxylase; Vitamin K-dependent gamma-carboxylase; vitamin K-dependent gamma-carboxylase; peptidyl-glutamate 4-carboxylase; vitamin K gamma glutamyl carboxylase; gamma-glutamyl carboxylase; Gamma-glutamyl carboxylase; Peptidyl-glutamate 4-carboxylase; Vitamin K gamma glutamyl carboxylase
products gene name :
GGCX
other gene names :
Ggcx; Ggcx
uniprot entry name :
VKGC_RAT
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GGCX (hereafter termed this analyte) in Rat serum, plasma and tissue homogenate samples.
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GGCX (hereafter termed this analyte) in Rat serum, plasma and tissue homogenate samples.
ncbi acc num :
NP_113944.1
ncbi gb acc num :
NM_031756.1
ncbi mol weight :
87,479 Da
ncbi pathways :
Gamma-carboxylation Of Protein Precursors Pathway (574336); Gamma-carboxylation, Transport, And Amino-terminal Cleavage Of Proteins Pathway (574335); Metabolism Of Proteins Pathway (574309); PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway (574334); Post-translational Protein Modification Pathway (574333)
ncbi summary :
catalyzes the posttranslational modification of glutamate to gamma-carboxyglutamate (Gla); may mediate functions of vitamin K-dependent proteins (VKDPs) [RGD, Feb 2006]
uniprot summary :
Function: Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. Catalytic activity: [Peptidyl]-4-carboxyglutamate + 2,3-epoxyphylloquinone + H2O = [peptidyl]-glutamate + CO2 + O2 + phylloquinone.