Human Enhancer of filamentation 1, NEDD9 ELISA Kit | MyBioSource MBS9337288 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Enhancer of filamentation 1, NEDD9 ELISA Kit

catalog :

MBS9337288

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9337288

products type :

ELISA Kit

products full name :

Human Enhancer of filamentation 1, NEDD9 ELISA Kit

products short name :

neural precursor cell expressed, developmentally down-regulated 9

products name syn :

Human Enhancer of filamentation 1 (NEDD9) ELISA kit; CAS-L; CAS2; CASL; CASS2; HEF1; dJ49G10.2; dJ761I2.1; Cas scaffolding protein family member 2; Crk-associated substrate related; cas-like docking; dJ49G10.2 (Enhancer of Filamentation 1 (HEF1) ) ; dJ761I2; neural precursor cell expressed; developmentally down-regulated 9

other names :

enhancer of filamentation 1 isoform 3; Enhancer of filamentation 1; enhancer of filamentation 1; cas-like docking; p130Cas-related protein; Enhancer of filamentation 1 p55; renal carcinoma antigen NY-REN-12; Cas scaffolding protein family member 2; Crk-associated substrate related protein Cas-L; neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; CRK-associated substrate-related protein; CAS-L; CasL; Cas scaffolding protein family member 2; Neural precursor cell expressed developmentally down-regulated protein 9; NEDD-9; Renal carcinoma antigen NY-REN-12; p105Cleaved into the following chain:Enhancer of filamentation 1 p55

products gene name :

NEDD9

other gene names :

NEDD9; NEDD9; CAS2; CASL; HEF1; CAS-L; CASS2; CASL; CASS2; hEF1; CAS-L; CasL; NEDD-9

uniprot entry name :

CASL_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma and Tissue Homogenate. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml. Assay Type: Sandwich

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of EF1 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

ncbi gi num :

215422375

ncbi acc num :

NP_001135865.1

ncbi gb acc num :

NM_001142393.1

uniprot acc num :

Q14511

ncbi mol weight :

92,861 Da

ncbi pathways :

B Cell Receptor Signaling Pathway (198909); T Cell Receptor Signaling Pathway (198862)

ncbi summary :

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

uniprot summary :

Cas-L: a widely expressed docking protein which plays a central coordinating role for tyrosine-kinase-based signaling in cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form. Phosphorylated following integrin beta-1, antigen receptor, or C1a calcitonin receptor signaling. Transformation of fibroblasts with v-ABL results in an increase in its tyrosine phosphorylation. Phosphorylated by focal adhesion kinase. Highly expressed in kidney, lung, and placenta. Also detected in T-cells, B-cells and diverse cell lines. Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold. Chromosomal Location of Human Ortholog: 6p24.2. Cellular Component: spindle pole; Golgi apparatus; focal adhesion; lamellipodium; cytoplasm; spindle; cell cortex; nucleus. Molecular Function: protein binding. Biological Process: integrin-mediated signaling pathway; mitosis; actin filament bundle formation; cell division; regulation of growth; cytoskeleton organization and biogenesis; cell adhesion; signal transduction

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage