product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Membrane protein MLC1, MLC1 ELISA Kit
catalog :
MBS9337225
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9337225
products type :
ELISA Kit
products full name :
Human Membrane protein MLC1, MLC1 ELISA Kit
products short name :
[megalencephalic leukoencephalopathy with subcortical cysts 1]
products name syn :
[Human Membrane protein MLC1 (MLC1) ELISA kit; RP3-355C18.4; KIAA0027; LVM; MLC; VL; megalencephalic leukoencephalopathy with subcortical cysts 1 gene product; megalencephalic leukoencephalopathy with subcortical cysts 1]
other names :
[membrane protein MLC1; Membrane protein MLC1; membrane protein MLC1; megalencephalic leukoencephalopathy with subcortical cysts 1]
products gene name :
[MLC1]
other gene names :
[MLC1; MLC1; VL; LVM; MLC; KIAA0027; WKL1]
uniprot entry name :
MLC1_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 31.2 ng/ml - 1000 ng/ml. Sensitivity: The sensitivity of this kit is 5.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MLC1 (hereafter termed this analyte) in undiluted original Human body fluids, tissue homogenates, secretions and feces samples.
ncbi gi num :
14589896
ncbi acc num :
NP_055981.1
ncbi gb acc num :
NM_015166.3
uniprot acc num :
Q15049
ncbi mol weight :
41,141 Da
ncbi summary :
The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
uniprot summary :
MLC1: Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx. Defects in MLC1 are a cause of leukoencephalopathy megalencephalic with subcortical cysts type 1 (MLC1). MLC1 is a syndrome of cerebral leukoencephalopathy and megalencephaly characterized by ataxia, spasticity, seizures, delay in motor development and mild mental retardation. The brain appears swollen on magnetic resonance imaging, with diffuse white- matter abnormalities and the invariable presence of subcortical cysts in frontal and temporal lobes. Protein type: Transporter; Membrane protein, multi-pass; Cell surface; Membrane protein, integral. Chromosomal Location of Human Ortholog: 22q13.33. Cellular Component: clathrin-coated vesicle; endoplasmic reticulum; lysosome; basolateral plasma membrane; early endosome; integral to membrane; caveola; intercellular junction; lipid raft; recycling endosome; perinuclear region of cytoplasm; cytoplasm; apical plasma membrane; plasma membrane; cytoplasmic vesicle; endosome. Molecular Function: protein binding; transporter activity; protein complex binding; protein transporter activity. Biological Process: vesicle-mediated transport; protein transport; transport; positive regulation of intracellular transport; ion transport; protein oligomerization; regulation of response to osmotic stress. Disease: Megalencephalic Leukoencephalopathy With Subcortical Cysts 1
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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