catalog number :
MBS9337206
products type :
ELISA Kit
products full name :
Human Myotubularin-related protein 14, MTMR14 ELISA Kit
products short name :
[myotubularin related protein 14]
products name syn :
[Human Myotubularin-related protein 14 (MTMR14) ELISA kit; C3orf29; FLJ22405; FLJ46453; FLJ90311; HJUMPY; hEDTP; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; NS5ATP4ABP1; egg-derived tyrosine phosphatase homolog; jumpy; myotubularin related protein 14]
other names :
[myotubularin-related protein 14 isoform 2; Myotubularin-related protein 14; myotubularin-related protein 14; jumpy; NS5ATP4ABP1; egg-derived tyrosine phosphatase homolog; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; myotubularin related protein 14; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; NS5ATP4ABP1; hJumpy]
products gene name :
[MTMR14]
other gene names :
[MTMR14; MTMR14; C3orf29; C3orf29; NS5ATP4ABP1]
uniprot entry name :
MTMRE_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MTMR14 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001070993.1
ncbi gb acc num :
NM_001077525.2
ncbi mol weight :
72,203 Da
ncbi pathways :
3-phosphoinositide Degradation Pathway (545349); 3-phosphoinositide Degradation Pathway (139488); D-myo-inositol-5-phosphate Metabolism Pathway (545315); D-myo-inositol-5-phosphate Metabolism Pathway (138601); Superpathway Of Inositol Phosphate Compounds (547492)
ncbi summary :
This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.[provided by RefSeq, Apr 2010]
uniprot summary :
MTMR14: Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3. Expressed in various tissues, including heart, skeletal muscle, placenta, liver, lung, kidney and pancreas. Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.1.3.-; Phosphatase, lipid; Protein phosphatase, tyrosine (non-receptor). Chromosomal Location of Human Ortholog: 3p26. Cellular Component: ruffle; perinuclear region of cytoplasm; cytosol. Molecular Function: phosphatidylinositol-3-phosphatase activity; protein tyrosine phosphatase activity. Biological Process: phospholipid metabolic process; phosphatidylinositol biosynthetic process. Disease: Myopathy, Centronuclear, 1
size4 :
10x96-Strip-Wells