Human Dynein heavy chain 5, axonemal, DNAH5 ELISA Kit | MyBioSource MBS9337198 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Dynein heavy chain 5, axonemal, DNAH5 ELISA Kit

catalog :

MBS9337198

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9337198

products type :

ELISA Kit

products full name :

Human Dynein heavy chain 5, axonemal, DNAH5 ELISA Kit

products short name :

[dynein, axonemal, heavy chain 5]

products name syn :

[Human Dynein heavy chain 5; axonemal (DNAH5) ELISA kit; CILD3; DNAHC5; FLJ46759; HL1; KIAA1603; KTGNR; PCD; axonemal beta dynein heavy chain 5; ciliary dynein heavy chain 5; dynein; axonemal; heavy polypeptide 5; dynein; axonemal; heavy chain 5]

other names :

[dynein heavy chain 5, axonemal; Dynein heavy chain 5, axonemal; dynein heavy chain 5, axonemal; ciliary dynein heavy chain 5; axonemal beta dynein heavy chain 5; dynein, axonemal, heavy polypeptide 5; dynein, axonemal, heavy chain 5; Axonemal beta dynein heavy chain 5; Ciliary dynein heavy chain 5]

products gene name :

[DNAH5]

other gene names :

[DNAH5; DNAH5; HL1; PCD; CILD3; KTGNR; DNAHC5; DNAHC5; HL1; KIAA1603]

uniprot entry name :

DYH5_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Human Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 62.5pg/ml-2000pg/ml. Sensitivity: 10pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of DMRT3 (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

ncbi gi num :

19115954

ncbi acc num :

NP_001360.1

ncbi gb acc num :

NM_001369.2

uniprot acc num :

Q8TE73

ncbi mol weight :

529,021 Da

ncbi summary :

This gene encodes a dynein protein, which is part of a microtubule-associated motor protein complex consisting of heavy, light, and intermediate chains. This protein is an axonemal heavy chain dynein. It functions as a force-generating protein with ATPase activity, whereby the release of ADP is thought to produce the force-producing power stroke. Mutations in this gene cause primary ciliary dyskinesia type 3, as well as Kartagener syndrome, which are both diseases due to ciliary defects. [provided by RefSeq, Oct 2009]

uniprot summary :

DNAH5: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of the cilia of ependymal cells lining the brain ventricles. Defects in DNAH5 are the cause of primary ciliary dyskinesia type 3 (CILD3). CILD3 is an autosomal recessive disorder characterized by axonemal abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit situs inversus, due to dysfunction of monocilia at the embryonic node and randomization of left-right body asymmetry. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Defects in DNAH5 are a cause of Kartagener syndrome (KTGS). KTGS is an autosomal recessive disorder characterized by the association of primary ciliary dyskinesia with situs inversus. Clinical features include recurrent respiratory infections, bronchiectasis, infertility, and lateral transposition of the viscera of the thorax and abdomen. The situs inversus is most often total, although it can be partial in some cases (isolated dextrocardia or isolated transposition of abdominal viscera). Belongs to the dynein heavy chain family. Protein type: Motor; Microtubule-binding; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 5p15.2. Cellular Component: microtubule; axonemal dynein complex; axoneme. Molecular Function: ATPase activity; microtubule motor activity; ATP binding. Biological Process: metabolic process; lateral ventricle development. Disease: Ciliary Dyskinesia, Primary, 3

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage